The importance of the erythrocyte distribution width/ albumin ratio in patients with chronic obstructive pulmonary disease exacerbation

被引:1
作者
Eraslan, Berrin Z. [1 ]
Cengiz, Sumeyye K. [1 ]
Sagmen, Seda B. [1 ]
Yalcinkaya, Kubra Z. [1 ]
Kiral, Nesrin [1 ]
Coemert, Sevda [1 ]
机构
[1] Univ Hlth Sci, Kartal Dr Lutfi Kirdar City Hosp, Dept Chest Dis, Istanbul, Turkiye
关键词
hospital length of stay; inflammation; red blood cell distribution width-albumin ratio; chronic obstructive pulmonary disease; COPD; CELL DISTRIBUTION WIDTH; AIRWAY INFLAMMATION; COPD EXACERBATIONS; BIOMARKER; MORTALITY; RISK;
D O I
10.15537/smj.2024.45.1.20230716
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: To investigate the relationship of the erythrocyte distribution width (RDW)/albumin ratio on hospital length of stay (LOS) and prognosis in patients hospitalized with chronic obstructive pulmonary disease (COPD) exacerbation. Methods: Patients hospitalized in our clinic for COPD exacerbation were retrospectively analyzed. Demographic characteristics, comorbidities, pulmonary function tests, arterial blood gas, history of hospitalization due to exacerbation in the last year, LOS, C -reactive protein, RDW, albumin, platelet counts, and 30 -day mortality status were recorded. Significant cut-off RDW/albumin ratio values that could predict hospitalization for 10 days or more were analyzed. Results: A total of 58 patients were included in our study. With a significant cut-off value of >= 5.22 for the RDW/albumin ratio to predict a duration of hospitalization of more than 10 days, a sensitivity of 68.42% and specificity of 74.36% were obtained. No significant association was found between the RDW/albumin ratio and 30 -day mortality (p=0.14). The RDW/albumin ratio (p=0.005) and mortality (p<0.001) were found to be higher in patients with an LOS of 10 days or more. The RDW/albumin ratio and mortality, which were statistically significant in patients hospitalized for 10 days or more, were analyzed using logistic regression, and no significant results were found. Conclusion: In further analysis results of patients hospitalized due to COPD exacerbation, there was no significant relationship between length of hospital stay, mortality, and the RDW/albumin ratio.
引用
收藏
页码:27 / 33
页数:7
相关论文
共 27 条
  • [1] [Anonymous], GLOBAL STRATEGY DIAG
  • [2] Severe hypoalbuminemia is a strong independent risk factor for acute respiratory failure in COPD: a nationwide cohort study
    Chen, Char-Wen
    Chen, Yih-Yuan
    Lu, Chin-Li
    Chen, Solomon Chih-Cheng
    Chen, Yi-Jen
    Lin, Ming-Shian
    Chen, Wei
    [J]. INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2015, 10 : 1147 - 1154
  • [3] Outcomes following acute exacerbation of severe chronic obstructive lung disease
    Connors, AF
    Dawson, NV
    Thomas, C
    Harrell, FE
    Desbiens, N
    Fulkerson, WJ
    Kussin, P
    Bellamy, P
    Goldman, L
    Knaus, WA
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1996, 154 (04) : 959 - 967
  • [4] Relation Between Red Cell Distribution Width and Clinical Outcomes After Acute Myocardial Infarction
    Dabbah, Saleem
    Hammerman, Haim
    Markiewicz, Walter
    Aronson, Doron
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 2010, 105 (03) : 312 - 317
  • [5] Serum albumin: Relationship to inflammation and nutrition
    Don, BR
    Kaysen, G
    [J]. SEMINARS IN DIALYSIS, 2004, 17 (06) : 432 - 437
  • [6] Airway inflammation during stable and acutely exacerbated chronic obstructive pulmonary disease
    Fujimoto, K
    Yasuo, M
    Urushibata, K
    Hanaoka, M
    Koizumi, T
    Kubo, K
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2005, 25 (04) : 640 - 646
  • [7] Factors affecting survival of hospitalised patients with COPD
    Gunen, H
    Hacievliyagil, SS
    Kosar, F
    Mutlu, LC
    Gulbas, G
    Pehlivan, E
    Sahin, I
    Kizkin, O
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2005, 26 (02) : 234 - 241
  • [8] The GOLD Summit on chronic obstructive pulmonary disease in low- and middle-income countries
    Halpin, D. M. G.
    Celli, B. R.
    Criner, G. J.
    Frith, P.
    Lopez Varela, M. V.
    Salvi, S.
    Vogelmeier, C. F.
    Chen, R.
    Mortimer, K.
    Montes de Oca, M.
    Aisanov, Z.
    Obaseki, D.
    Decker, R.
    Agusti, A.
    [J]. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 2019, 23 (11) : 1131 - 1141
  • [9] Case fatality of COPD exacerbations: a meta-analysis and statistical modelling approach
    Hoogendoorn, M.
    Hoogenveen, R. T.
    Moelken, M. P. Rutten-van
    Vestbo, J.
    Feenstra, T. L.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2011, 37 (03) : 508 - 515
  • [10] The role of increased red cell distribution width as a negative prognostic marker in patients with COPD
    Karampitsakos, Theodoros
    Dimakou, Katerina
    Papaioannou, Ourania
    Chrysikos, Serafeim
    Kaponi, Maria
    Bouros, Demosthenes
    Tzouvelekis, Argyrios
    Hillas, Georgios
    [J]. PULMONARY PHARMACOLOGY & THERAPEUTICS, 2020, 60