Epidemics and society - A multiscale vision from the small world to the globally interconnected world

被引:11
作者
Burini, Diletta [1 ]
Knopoff, Damian A. [2 ,3 ]
机构
[1] Liceo Statale Class & Musicale A Mariotti, I-06123 Perugia, Italy
[2] Univ Deusto, Fac Engn, Avda Univ 24, Bilbao 48007, Spain
[3] Ctr Invest & Estudios Matemat, CONICET, Medina Allende S-N, RA-5000 Cordoba, Argentina
关键词
Pandemics; immune competition; multiscale modeling; Darwinist dynamics; variants; complex networks; DISEASE CONTAGION; MATHEMATICS; MODEL;
D O I
10.1142/S0218202524500295
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
This paper shows how a new theory of epidemics can be developed for viral pandemics in a globally interconnected world. The study of the in-host dynamics and, in parallel, the spatial diffusion of epidemics defines the goal of our work, which looks ahead to new mathematical tools to model epidemics beyond the traditional approach of population dynamics. The approach takes into account the evolutionary nature of the virus, which can generate pseudo-Darwinian mutations and selection, while learning the presence of the virus and activating adaptive immunity. The study of immune competition plays a key role in both the in-host dynamics and the contagion dynamics.
引用
收藏
页码:1567 / 1596
页数:30
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