Neutronics Analyses of the Radiation Field at the Accelerator-Based Neutron Source of Nagoya University for the BNCT Study

被引：4

作者：

Nishitani, Takeo ^{[1
]}

Yoshihashi, Sachiko ^{[1
]}

Tanagami, Yuuki ^{[1
]}

Tsuchida, Kazuki ^{[1
]}

Honda, Shogo ^{[1
]}

Yamazaki, Atsushi ^{[1
]}

Watanabe, Kenichi ^{[2
]}

Kiyanagi, Yoshiaki ^{[3
]}

Uritani, Akira ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Engn, Furo cho,Chikusa ku, Nagoya 4648603, Japan

[2] Kyushu Univ, Grad Sch, 744 Motooka, Fukuoka 8190395, Japan

[3] Hokkaido Univ, Fac Engn, Sapporo, Hokkaido 0608628, Japan

来源：

JOURNAL OF NUCLEAR ENGINEERING | 2022年 / 3卷 / 03期

关键词：

boron neutron capture therapy; accelerator-based neutron source; PHITS code; radiation therapy; Monte Carlo method; neutron dosimetry; NUCLEAR-SCIENCE; LIBRARY;

D O I：

10.3390/jne3030012

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

The Nagoya University Accelerator-driven Neutron Source (NUANS) is an accelerator-based neutron source by 7Li(p,n)7Be reaction with a 2.8 MeV proton beam up to 15 mA. The fast neutrons are moderated and shaped to beam with a Beam Shaping Assembly (BSA). NUANS is aiming at the basic study of the Boron Neutron Capture Therapy (BNCT) such as an in vitro cell-based irradiation experiment using a water phantom. Moreover, the BSA is developed as a prototype of one for human treatment. We have evaluated the radiation field of NUANS by a Monte Carlo code PHITS. It is confirmed that the radiation characteristics at the BNCT outlet meet the requirement of IAEA TECDOC-1223. Additionally, the radiation field in the water phantom located just in front of the BSA outlet is calculated. In the in vitro irradiation experiment, the boron dose of 30 Gy-eq, which is the dose to kill tumor cells, is expected for 20 min of irradiation at the beam current of 15 mA.

引用

页码：222 / 232

页数：11

共 21 条

[21] First experimental verification of the neutron field of Nagoya University Accelerator-driven neutron source for boron neutron capture therapy [J].

Watanabe, Kenichi ;

Yoshihashi, Sachiko ;

Ishikawa, Akihisa ;

Honda, Shogo ;

Yamazaki, Atsushi ;

Tsurita, Yukio ;

Uritani, Akira ;

Tsuchida, Kazuki ;

Kiyanagi, Yoshiaki .

APPLIED RADIATION AND ISOTOPES, 2021, 168

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