Olfactory Dysfunction in Healthcare Workers with COVID-19: Prevalence and Associated Factors

被引:0
作者
Imene, Kacem [1 ,2 ]
Mohamed, Kahloul [1 ,3 ]
Amal, Ghenim [1 ,2 ]
Mohamed, Ajmi [1 ,3 ]
Asma, Chouchane [1 ,2 ]
Asma, Aloui [1 ,2 ]
Wael, Khalefa [4 ]
Kalboussi, H. [1 ,2 ]
Olfa, El Maalel [1 ,2 ]
Walid, Naija [1 ,3 ]
Maher, Maoua [1 ,2 ]
Nejib, Mrizak [1 ,2 ]
机构
[1] Univ Sousse, Fac Med Sousse, Sousse 4000, Tunisia
[2] Univ Hosp Farhat Hached, Dept Occupat Med, Sousse, Tunisia
[3] Univ Hosp Sahloul, Dept Anesthesia & Intens Care, Sousse, Tunisia
[4] Fac Med Sousse, Family & Community Med Dept, Sousse, Tunisia
来源
RECENT ADVANCES IN INFLAMMATION & ALLERGY DRUG DISCOVERY | 2024年 / 18卷 / 01期
关键词
Persisted; therapeutic options; symptoms; pauci-asymptomatic; olfactory dysfunction; PCR; CLINICAL CHARACTERISTICS; SARS-COV-2; ANOSMIA; DISEASE;
D O I
10.2174/0127722708249126231006061438
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background The COVID-19 pandemic is a real global health crisis. Its clinical presentation has evolved over time with an increasing number of symptoms. Olfactory dysfunction (OD) has recently been recognized as a frequent symptom relevant to screening for COVID-19, especially in pauci-asymptomatic forms. However, the underlying mechanisms of OD are not yet fully understood.Aim To determine the prevalence of OD in healthcare workers with SARS-CoV-2 and to identify its associated factors.Methods This is a cross-sectional, analytical study, carried out during a period of six months and including all healthcare workers at Farhat Hached Academic Hospital (Tunisia) who were diagnosed with SARS-CoV-2 by PCR, RAT, or chest CT scan.Results A total of 474 healthcare workers were included, representing a participation rate of 85.4%. The mean age was 41.02 +/- 10.67 years with a sex ratio of 0.2. The distribution of this population by department noted that it was mainly maternity (13.9%). The most presented workstation was nursing (31.4%). OD represented 39.2% of the reasons for consultation. Hospitalization was indicated in 16 patients (3.4%). The average duration of hospitalization was 8.87 +/- 7.8 days. The average time off work was 17.04 +/- 11.6 days. OD persisted for more than 90 days in 35 patients (7.4%). After multiple binary logistic regression, OD was statistically associated with female gender (p =0.001; OR 95% CI: 2.46 [1.4-4.2]) and blue-collar occupational category (p =0.002; OR IC95%:3.1 [1.5-6.5]). A significant association was also noted between OD and professional seniority and absence from work duration (p =0.019; OR 95% CI: 0.97 [0.95-0.99] and p =0.03; OR 95% CI: 0.97 [0.95-0.99]) respectively.Conclusion OD is common in COVID-19 patients. The identification of its associated factors may contribute to enhancing the understanding of its mechanism and drive therapeutic options.
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页码:67 / 77
页数:11
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