Associations of Cognitive Impairment with All-Cause and Cardiovascular Mortality Among Individuals with Diabetes: A Prospective Cohort Study

被引:2
作者
Shang, Yanchang [1 ,2 ,4 ]
Wang, Shuhui [3 ]
Wei, Chao [1 ,2 ]
Xie, Hengge [1 ,2 ,4 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Med Ctr 2, Dept Geriatr Neurol, Beijing, Peoples R China
[2] Chinese Peoples Liberat Army Gen Hosp, Natl Clin Res Ctr Geriatr Dis, Beijing, Peoples R China
[3] Capital Med Univ, Beijing Friendship Hosp, Dept Neurol, Beijing, Peoples R China
[4] Chinese Peoples Liberat Army Gen Hosp, Dept Geriatr Neurol, Fuxing Rd 28, Beijing 100853, Peoples R China
关键词
diabetes; cognitive impairment; mortality; prospective study; EXCESS MORTALITY; RISK; SURVIVAL; DISEASE;
D O I
10.1177/07334648241241392
中图分类号
R4 [临床医学]; R592 [老年病学];
学科分类号
1002 ; 100203 ; 100602 ;
摘要
This study explored the association between diabetes, cognitive imFpairment (CI), and mortality in a cohort of 2931 individuals aged 60 and above from the 2011 to 2014 NHANES. Mortality data was gathered through 2019, and multivariable Cox proportional hazards models were used to determine the association between diabetes, CI, and mortality adjusting for sociodemographic characteristics, lifestyle factors, and comorbidity conditions. The study spanned up to 9.17 years, observing 579 deaths, with individuals having both diabetes and CI showing the highest all-cause mortality (23.6 events per 100 patient-years). Adjusted analysis revealed a 2.34-fold higher risk of all-cause mortality for this group, surpassing those with diabetes or CI alone. These results held after a series of stratified and sensitivity analyses. In conclusion, CI was linked to higher all-cause mortality in individuals with diabetes, emphasizing the need to address cognitive dysfunction in diabetic patients.
引用
收藏
页码:1449 / 1460
页数:12
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