Analytical framework for end-to-end channel capacity in molecular communication system

The molecular communication system (MCS) is mainly based on the design structure of the nanodevices which are employed as nano-transmitter (Nano-TX) and nano-receiver (Nano-RX), owing to the limited drug-reservoir capacity. The current work addresses the physical design of such nanodevices and the coordination of molecular communication to accomplish an end-to-end capacity system model, which can be employed in the targeted drug delivery system (TDDS). In MCS, Nano-RX is a spherical structure with a cylindrical shell with adapting receptors that enables an increase in the received number of drug molecules according to the transmission rate. On the other hand, the more realistic structure of Nano-TX is a cylindrical reservoir capable of controlling the emitted nanocarriers in the blood vessel. The analytical framework and the performance of the proposed MCS are presented by using a compartmental model while a closed-form expression of the proposed end-to-end channel capacity is obtained. The performance evaluation is evaluated by applying network performance metrics such as channel capacity, throughput, and efficiency. The simulation results show that the proposed model can enhance the delivery of the therapeutic dose and thus minimize the side effects on healthy cells compared with conventional schemes. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.