The role of exercise in sickle cell anemia management: a narrative review of current evidence

被引：0
作者：
Zimakor Ewuzie [1 ]
Chimezirim Ezeano [2 ]
Soomro Zara [2 ]
Vohra Aaishah [2 ]
Nicholas Aderinto [3 ]
机构：
[1] Cygnet Hospital,Health Science Center
[2] University of North Texas,Department of Medicine and Surgery
[3] Ladoke Akintola University of Technology,undefined
[4] Ladoke Akintola University of Technology,undefined
来源：
Discover Medicine | / 1卷 / 1期
关键词：
Sickle cell anemia; Structured exercise interventions; Physical fitness; Quality of life; Clinical outcomes;
D O I：
10.1007/s44337-024-00047-1
中图分类号：
学科分类号：
摘要：
This review explores the efficacy of structured exercise interventions in improving physical fitness and quality of life in adults with sickle cell anemia (SCA). SCA is a genetic disorder characterized by abnormal hemoglobin production, leading to complications such as vaso-occlusive crises and anemia. Despite advances in management, individuals with SCA often experience reduced physical functioning and diminished quality of life. Exercise has been shown to improve cardiovascular fitness, muscle strength, and overall well-being in individuals with chronic illnesses. The review critically evaluates 11 studies investigating the effects of structured exercise programs on physical fitness and quality of life outcomes in adults with SCA. Findings suggest that structured exercise interventions can improve this population's cardiovascular fitness, muscle strength, and quality of life. However, gaps in research, such as the need for long-term studies and optimal exercise prescription, still need to be addressed. Future research should address these gaps to inform evidence-based exercise guidelines for individuals with SCA.
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