Synthesis of Spiro[pyrrole-2,5′-pyrrolo[2,3-d]pyrimidines] by Reaction of Pyrrolobenzoxazinetriones with 6-Amino-1,3-dimethyluracil

被引：1

作者：

Kobelev, A. I. ^{[1
]}

Dmitriev, M. V. ^{[1
]}

Maslivets, A. N. ^{[1
]}

机构：

[1] Perm State Univ, Perm 614990, Russia

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 60卷 / 04期

关键词：

hetareno[e]pyrrole-2,3-diones; pyrrolobenzoxazinetriones; 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 6-aminouracil; spiro[pyrrole-2,3 '-pyrroles; spiro[pyrrole-2,5 '-pyrrolo[2,3-d]pyrimidines; X-ray analysis;

D O I：

10.1134/S1070428024040109

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones reacted with 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-diones to give 3-aroyl-4-hydroxy-1-(2-hydroxyaryl)-1 ',3 '-dimethylspiro[pyrrole-2,5 '-pyrrolo[2,3-d]pyrimidine]-2 ',4 ',5,6 '(1H,1 ' H,3 ' H,7 ' H)-tetraones. The product structure was confirmed by X-ray analysis. The described reaction provides a simple route to the difficultly accessible spiro[pyrrole-2,5 '-pyrrolo[2,3-d]pyrimidine] heterocyclic system.

引用

页码：632 / 637

页数：6

共 50 条

[21] A convenient synthesis of pyrrolo[2,3-b]pyridines and pyrido[2′,3′:5,4]pyrrolo[2,3-d]pyrimidines
Abdel-Mohsen, Shawkat A.
Geies, Ahmed A.
MONATSHEFTE FUR CHEMIE, 2008, 139 (10): : 1233 - 1240
[22] PYRIDO[2,3-D]PYRIMIDINES .8. SYNTHESIS OF PYRROLO(2',3'/4,5)PYRIDO[2,3-D]PIRIMIDINES
BISTRYAKOVA, ID
SMIRNOVA, NM
SAFONOVA, TS
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (06): : 800 - 803
[23] NEW PYRROLE DERIVATIVES - SYNTHESIS OF 4-AMINO-6-METHYLTHIO-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILES
PECH, R
BOHM, R
HENKEL, L
ZEITSCHRIFT FUR CHEMIE, 1990, 30 (07): : 248 - 249
[24] Facile Methods for the Synthesis of 5-Aryl and 5-Iodo Pyrrolo[2,3-d]pyrimidines
Rao, K. Venkata
Prasad, M. Raghu
Rao, A. Raghuram
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 : E380 - E383
[25] SYNTHESIS OF SOME 5-(SUBSTITUTED AMINO)THIENO[2,3-D]PYRIMIDINES
TUMKYAVICHIUS, S
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1995, (07): : 986 - 990
[26] SYNTHESIS OF 7-DEAZATRIACANTHINE AND RESTRICTED ROTATION OF AMINO-GROUPS IN PYRROLO[2,3-D]PYRIMIDINES
SEELA, F
BUSSMANN, W
NUCLEOSIDES & NUCLEOTIDES, 1984, 3 (02): : 195 - 206
[27] Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3-d]pyrimidines
Yu. V. Popova
D. V. Osipov
V. A. Osyanin
Yu. N. Klimochkin
Russian Journal of Organic Chemistry, 2017, 53 : 599 - 603
[28] Reaction of trifluoroacetylchromenes with 6-aminouracils. Synthesis of pyrido[2,3-d]pyrimidines
Popova, Yu. V.
Osipov, D. V.
Osyanin, V. A.
Klimochkin, Yu. N.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 53 (04) : 599 - 603
[29] Synthesis of Spiro(pyrrol-2,5'-pyrrolo[2,3-d]pyrimidine)-2',4',5,6'-tetraones by the Reaction of Pyrrolo[2,1-c][1,4]oxazinetriones with 6-Aminopyrimidine-2,4-diones
Tretyakov, N. A.
Dmitriev, M. V.
Maslivets, A. N.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 59 (02) : 237 - 242
[30] Synthesis of novel spiro-fused pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidines
Fazlelahi, Hadi Z.
Moghadam, Peyman N.
Baradarani, Mehdi M.
Joule, John A.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 57 (10) : 3673 - 3684

← 1 2 3 4 5 →