Fabry disease is a rare genetic disease caused by a deficiency of alpha-galactosidase A gene (alpha-Gal A). Two intravenous enzymes administered every two weeks, agalsidase alfa and beta can slow disease progression and increase survival if administered early, before organ damage occurs. In this case report, we present a patient with a history of anaphylaxis to agalsidase beta who was successfully treated with agalsidase alfa.
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UCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, EnglandUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Mehta, Atul
Beck, Michael
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Univ Childrens Hosp, Mainz, GermanyUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Beck, Michael
Kampmann, Christoph
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Univ Childrens Hosp, Mainz, GermanyUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Kampmann, Christoph
Frustaci, Andrea
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Univ Roma La Sapienza, Heart & Great Vessels Attilio Reale Dept, Rome, ItalyUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Frustaci, Andrea
Germain, Dominique P.
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Univ Versailles St Quentin Yvelines, Hop Raymond Poincare, AP HP, UF Genet Med, Garches, FranceUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Germain, Dominique P.
Pastores, Gregory M.
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NYU, Sch Med, Dept Neurol & Pediat, New York, NY USAUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England
Pastores, Gregory M.
Sunder-Plassmann, Gere
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Dept Internal Med 3, Div Nephrol & Dialysis, Vienna, AustriaUCL Royal Free & Univ Coll Med Sch, Dept Acad Haematol, London NW3 2QG, England