COPPER(II) COMPLEXES BASED ON 2,2'-BIPYRIDINE AND 1,10-PHENANTHROLINE AS POTENTIAL OBJECTS FOR DEVELOPING ANTITUMOR DRUGS

被引：8
作者：
Golubeva, Yu. A. [1 ]
Lider, E. V. [1 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Nikolaev Inst Inorgan Chem, Novosibirsk, Russia
来源：
JOURNAL OF STRUCTURAL CHEMISTRY | 2024年 / 65卷 / 06期
基金：
俄罗斯科学基金会;
关键词：
copper complexes; 1,10-phenanthroline; 2,2 '-bipyridine; cytotoxic activity; in vivo studies; IN-VITRO CYTOTOXICITY; DNA-BINDING; CRYSTAL-STRUCTURE; METAL-COMPLEXES; STRUCTURAL-CHARACTERIZATION; BIOLOGICAL-ACTIVITIES; SUPEROXIDE-DISMUTASE; ANTICANCER ACTIVITY; II COMPLEXES; NUCLEASE ACTIVITY;
D O I：
10.1134/S0022476624060088
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The review is devoted to copper coordination compounds based on 2,2 '-bipyridine / 1,10-phenanthroline and diverse N-, O-, S-donor ligands exhibiting cytotoxic properties. Therefore, they can be a starting platform for developing antitumor drugs. The review covers the structural aspects of the complexes, the features of their cytotoxic activity and its mechanism, as well as in vivo studies.
引用
收藏
页码：1159 / 1209
页数：51
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