Rethinking the application of nanoparticles in women's reproductive health and assisted reproduction

被引：0
作者：
Davis, Emily H. S. [1 ]
Jones, Celine [1 ]
Coward, Kevin [1 ]
机构：
[1] Univ Oxford, John Radcliffe Hosp, Womens Ctr, Nuffield Dept Womens & Reprod Hlth, Oxford OX3 9DU, England
来源：
NANOMEDICINE | 2024年 / 19卷 / 14期
关键词：
assisted reproductive technology; endometriosis; nanoparticles; polycystic ovary syndrome; sexually transmitted infections; uterine fibroids; women's reproductive health; POLYCYSTIC-OVARY-SYNDROME; MESOPOROUS SILICA NANOPARTICLES; SILVER NANOPARTICLES; MAGNETIC NANOPARTICLES; UTERINE LEIOMYOMA; GENE-THERAPY; ENDOMETRIOSIS; CELLS; APOPTOSIS; PATHOGENESIS;
D O I：
10.2217/nnm-2023-0346
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Nanoparticles and nanotechnology may present opportunities to revolutionize the prevention, treatment and diagnosis of a range of reproductive health conditions in women. These technologies are also used to improve outcomes of assisted reproductive technology. We highlight a range of these potential clinical uses of nanoparticles for polycystic ovary syndrome, endometriosis, uterine fibroids and sexually transmitted infections, considering in vitro and in vivo studies along with clinical trials. In addition, we discuss applications of nanoparticles in assisted reproductive technology, including sperm loading, gamete and embryo preservation and preventing preterm birth. Finally, we present some of the concerns associated with the medical use of nanoparticles, identifying routes for further exploration before nanoparticles can be applied to women's reproductive health in the clinic. What opportunities do nanoparticles present to revolutionize the prevention, treatment and diagnosis of reproductive health conditions in women and improve outcomes of assisted reproductive technology?
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页码：1231 / 1251
页数：21
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