Cutting-edge approaches for targeted drug delivery in breast cancer: beyond conventional therapies

被引:18
|
作者
Chaudhari, Ramesh [1 ]
Patel, Vishva [1 ]
Kumar, Ashutosh [1 ]
机构
[1] Ahmedabad Univ, Sch Arts & Sci, Biol & Life Sci, Cent Campus, Ahmadabad 380009, Gujarat, India
来源
NANOSCALE ADVANCES | 2024年 / 6卷 / 09期
关键词
TUMOR MICROENVIRONMENT; MACROMOLECULAR THERAPEUTICS; MAGNETIC NANOPARTICLES; SUBTYPES; PEPTIDE; WOMEN; PLUS; NANOMEDICINE; PERMEABILITY; CHEMOTHERAPY;
D O I
10.1039/d4na00086b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Breast cancer is a global health challenge with staggering statistics underscoring its pervasive impact. The burden of this disease is measured in terms of its prevalence and the challenges it poses to healthcare systems, necessitating a closer look at its epidemiology and impact. Current breast cancer treatments, including surgery, chemotherapy, radiation therapy, and targeted therapies, have made significant strides in improving patient outcomes. However, they are not without limitations, often leading to adverse effects and the development of drug resistance. This comprehensive review delves into the complex landscape of breast cancer, including its incidence, current treatment modalities, and the inherent limitations of existing therapeutic approaches. It also sheds light on the promising role of nanotechnology, encompassing both inorganic and organic nanoparticles equipped with the ability to selectively deliver therapeutic agents to tumor sites, in the battle against breast cancer. The review also addresses the emerging therapies, their associated challenges, and the future prospects of targeted drug delivery in breast cancer management. Discover the groundbreaking potential of nanotech-based targeted delivery in breast cancer therapy. Our review showcases how this innovative precision medicine approach can revolutionise treatment and improve patient outcomes.
引用
收藏
页码:2270 / 2286
页数:17
相关论文
共 50 条
  • [41] Emerging targeted drug delivery strategies toward ovarian cancer
    Wang, Zhe
    Meng, Fenghua
    Zhong, Zhiyuan
    ADVANCED DRUG DELIVERY REVIEWS, 2021, 178
  • [42] Nanoceria-Mediated Drug Delivery for Targeted Photodynamic Therapy on Drug-Resistant Breast Cancer
    Li, Hong
    Liu, Cong
    Zeng, Yi-Ping
    Hao, Yu -Hui
    Huang, Jia-Wei
    Yang, Zhang-You
    Li, Rong
    ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (46) : 31510 - 31523
  • [43] Advances in inorganic nanoparticles-based drug delivery in targeted breast cancer theranostics
    Rahimkhoei, Vahid
    Alzaidy, Asaad H.
    Abed, May Jaleel
    Rashki, Somaye
    Salavati-Niasari, Masoud
    ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2024, 329
  • [44] Innovative nanodelivery systems for targeted breast cancer therapy: overcoming drug delivery challenges and exploring future perspectives
    Su, Dandan
    Lai, Xiaolin
    Lin, Zhizhe
    Xu, Youfa
    Fu, Zhiqin
    Chen, Jianming
    Wu, Xin
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2025,
  • [45] Breast Cancer Bone Metastasis: A Narrative Review of Emerging Targeted Drug Delivery Systems
    Shao, Huimin
    Varamini, Pegah
    CELLS, 2022, 11 (03)
  • [46] Targeted Drug Delivery Systems Mediated by a Novel Peptide in Breast Cancer Therapy and Imaging
    Lu, Ruei-Min
    Chen, Min-Shan
    Chang, De-Kuan
    Chiu, Chien-Yu
    Lin, Wei-Chuan
    Yan, Shin-Long
    Wang, Yi-Ping
    Kuo, Yuan-Sung
    Yeh, Chen-Yun
    Lo, Albert
    Wu, Han-Chung
    PLOS ONE, 2013, 8 (06):
  • [47] Better Together: Targeted Combination Therapies in Breast Cancer
    Zanardi, Elisa
    Bregni, Giacomo
    de Braud, Filippo
    Di Cosimo, Serena
    SEMINARS IN ONCOLOGY, 2015, 42 (06) : 887 - 895
  • [48] Metaplastic breast carcinoma: Current therapeutic approaches and novel targeted therapies
    Drekolias, Dimitrios
    Mamounas, Eleftherios P.
    BREAST JOURNAL, 2019, 25 (06) : 1192 - 1197
  • [49] Nanotherapeutic approaches to overcome distinct drug resistance barriers in models of breast cancer
    Saha, Tanmoy
    Mondal, Jayanta
    Khiste, Sachin
    Lusic, Hrvoje
    Hu, Zhang-Wei
    Jayabalan, Ruparoshni
    Hodgetts, Kevin J.
    Jang, HaeLin
    Sengupta, Shiladitya
    Lee, Somin Eunice
    Park, Younggeun
    Lee, Luke P.
    Goldman, Aaron
    NANOPHOTONICS, 2021, 10 (12) : 3063 - 3073
  • [50] Targeted Therapies in Triple-Negative Breast Cancer
    Marme, Frederik
    Schneeweiss, Andreas
    BREAST CARE, 2015, 10 (03) : 159 - 166