Frailty in the cardiac intensive care unit: assessment and impact

被引:4
作者
Moumneh, Mohamad B. [1 ]
Jamil, Yasser [2 ]
Kalra, Kriti [1 ]
Ijaz, Naila [1 ]
Campbell, Greta [3 ]
Kochar, Ajar [3 ]
Nanna, Michael G. [4 ]
van Diepen, Sean [5 ]
Damluji, Abdulla A. [1 ,5 ,6 ]
机构
[1] Inova Ctr Outcomes Res Inova Heart & Vasc, 3300 Gallows Rd, Falls Church, VA 22042 USA
[2] Yale Sch Med, Dept Med, 333 Cedar St, New Haven, CT 06510 USA
[3] Brigham & Womens Hosp, Dept Cardiovasc Med, 75 Francis St, Boston, MA 02115 USA
[4] Yale Univ, Dept Med, Div Cardiol, Sch Med, 333 Cedar St, New Haven, CT 06510 USA
[5] Univ Alberta, Div Crit Care, 116 St & 85 Ave, Edmonton, AB T6G 2R3, Canada
[6] Johns Hopkins Univ, Dept Med, Div Cardiol, Sch Med, 733 N Broadway, Baltimore, MD 21205 USA
关键词
Ageing; Frailty; Older adults; Cardiovascular disease; Cardiac critical illness; CRITICALLY-ILL PATIENTS; QUALITY-OF-LIFE; OLDER-ADULTS; CRITICAL ILLNESS; MECHANICAL VENTILATION; MORTALITY; ASSOCIATION; SEDATION; DELIRIUM; ICU;
D O I
10.1093/ehjacc/zuae039
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Frailty, a clinical syndrome of increased vulnerability, due to diminished cognitive, physical, and physiological reserves is a growing concern in the cardiac intensive care unit (CICU). It contributes to morbidity, mortality, and complications and often exerts a bidirectional association with cardiovascular disease. Although it predominately affects older adults, frailty can also be observed in younger patients <65 years of age, with approximately 30% of those admitted in CICU are frail. Acute cardiovascular illness can also impair physical and cognitive functioning among survivors and these survivors often suffer from frailty and functional declines post-CICU discharge. Patients with frailty in the CICU often have higher comorbidity burden, and they are less likely to receive optimal therapy for their acute cardiovascular conditions. Given the significance of this geriatric syndrome, this review will focus on assessment, clinical outcomes, and interventions, in an attempt to establish appropriate assessment, management, and resource utilization in frail patients during and after CICU admission.
引用
收藏
页码:506 / 514
页数:9
相关论文
共 93 条
[1]   Non-pharmacological interventions to prevent or treat delirium in older patients: Clinical practice recommendations the SENATOR-ONTOP series [J].
Abraha, Iosief ;
Rimland, J. M. ;
Trotta, F. ;
Pierini, V. ;
Cruz-Jentoft, A. ;
Soiza, R. ;
O'Mahony, D. ;
Cherubini, A. .
JOURNAL OF NUTRITION HEALTH & AGING, 2016, 20 (09) :927-936
[2]   Frailty in Older Adults Undergoing Aortic Valve Replacement The FRAILTY-AVR Study [J].
Afilalo, Jonathan ;
Lauck, Sandra ;
Kim, Dae H. ;
Lefevre, Thierry ;
Piazza, Nicolo ;
Lachapelle, Kevin ;
Martucci, Giuseppe ;
Lamy, Andre ;
Labinaz, Marino ;
Peterson, Mark D. ;
Arora, Rakesh C. ;
Noiseux, Nicolas ;
Rassi, Andrew ;
Palacios, Igor F. ;
Genereux, Philippe ;
Lindman, Brian R. ;
Asgar, Anita W. ;
Kim, Caroline A. ;
Trnkus, Amanda ;
Morais, Jose A. ;
Langlois, Yves ;
Rudski, Lawrence G. ;
Morin, Jean-Francois ;
Popma, Jeffrey J. ;
Webb, John G. ;
Perrault, Louis P. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2017, 70 (06) :689-700
[3]   Frailty as a predictor of short- and long-term mortality in critically ill older medical patients [J].
Alberto Silva-Obregon, J. ;
Quintana-Diaz, Manuel ;
Saboya-Sanchez, Sonia ;
Marian-Crespo, Carlos ;
Angel Romera-Ortega, M. ;
Chamorro-Jambrina, Carlos ;
Estrella-Alonso, Alfonso ;
Maria Andres-Esteban, Eva .
JOURNAL OF CRITICAL CARE, 2020, 55 :79-85
[4]   A prospective multicenter cohort study of frailty in younger critically ill patients [J].
Bagshaw, M. ;
Majumdar, Sumit R. ;
Rolfson, Darryl B. ;
Ibrahim, Quazi ;
McDermid, Robert C. ;
Stelfox, H. Tom .
CRITICAL CARE, 2016, 20
[5]   Long-Term Association Between Frailty and Health-Related Quality of Life Among Survivors of Critical Illness: A Prospective Multicenter Cohort Study [J].
Bagshaw, Sean M. ;
Stelfox, H. Thomas ;
Johnson, Jeffrey A. ;
McDermid, Robert C. ;
Rolfson, Darryl B. ;
Tsuyuki, Ross T. ;
Ibrahim, Quazi ;
Majumdar, Sumit R. .
CRITICAL CARE MEDICINE, 2015, 43 (05) :973-982
[6]   Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study [J].
Bagshaw, Sean M. ;
Stelfox, H. Thomas ;
McDermid, Robert C. ;
Rolfson, Darryl B. ;
Tsuyuki, Ross T. ;
Baig, Nadia ;
Artiuch, Barbara ;
Ibrahim, Quazi ;
Stollery, Daniel E. ;
Rokosh, Ella ;
Majumdar, Sumit R. .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2014, 186 (02) :E95-E102
[7]   Early activity is feasible and safe in respiratory failure patients [J].
Bailey, Polly ;
Thomsen, George E. ;
Spuhler, Vicki J. ;
Blair, Robert ;
Jewkes, James ;
Bezdjian, Louise ;
Veale, Kristy ;
Rodriquez, Larissa ;
Hopkins, Ramona O. .
CRITICAL CARE MEDICINE, 2007, 35 (01) :139-145
[8]   The feasibility of measuring frailty to predict disability and mortality in older medical intensive care unit survivors [J].
Baldwin, Matthew R. ;
Reid, M. Cary ;
Westlake, Amanda A. ;
Rowe, John W. ;
Granieri, Evelyn C. ;
Wunsch, Hannah ;
Thuy-Tien Dam ;
Rabinowitz, Daniel ;
Goldstein, Nathan E. ;
Maurer, Mathew S. ;
Lederer, David J. .
JOURNAL OF CRITICAL CARE, 2014, 29 (03) :401-408
[9]   Is There an Association Between Metformin Exposure and Frailty? [J].
Baskaran, Dhanya ;
Aparicio-Ugarriza, Raquel ;
Ferri-Guerra, Juliana ;
Milyani, Raneem ;
Florez, Hermes ;
Ruiz, Jorge G. .
GERONTOLOGY AND GERIATRIC MEDICINE, 2020, 6
[10]   Optimizing Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older Adults (OPERAM): cluster randomised controlled trial [J].
Blum, Manuel R. ;
Sallevelt, Bastiaan T. G. M. ;
Spinewine, Anne ;
O'Mahony, Denis ;
Moutzouri, Elisavet ;
Feller, Martin ;
Baumgartner, Christine ;
Roumet, Marie ;
Jungo, Katharina Tabea ;
Schwab, Nathalie ;
Bretagne, Lisa ;
Beglinger, Shanthi ;
Aubert, Carole E. ;
Wilting, Ingeborg ;
Thevelin, Stefanie ;
Murphy, Kevin ;
Huibers, Corlina J. A. ;
Drenth-van Maanen, A. Clara ;
Boland, Benoit ;
Crowley, Erin ;
Eichenberger, Anne ;
Meulendijk, Michiel ;
Jennings, Emma ;
Adam, Luise ;
Roos, Marvin J. ;
Gleeson, Laura ;
Shen, Zhengru ;
Marien, Sophie ;
Meinders, Arend-Jan ;
Baretella, Oliver ;
Netzer, Seraina ;
de Montmollin, Maria ;
Fournier, Anne ;
Mouzon, Ariane ;
O'Mahony, Cian ;
Aujesky, Drahomir ;
Mavridis, Dimitris ;
Byrne, Stephen ;
Jansen, Paul A. F. ;
Schwenkglenks, Matthias ;
Spruit, Marco ;
Dalleur, Olivia ;
Knol, Wilma ;
Trelle, Sven ;
Rodondi, Nicolas .
BMJ-BRITISH MEDICAL JOURNAL, 2021, 374