The relationship between acrochordons, obesity, and metabolic syndrome in the pediatric population: A retrospective cohort study

被引:0
作者
Greene, Rachel K. [1 ]
Gangidi, Suma [2 ]
Zhao, Raymond [3 ]
Nelson, Jessie M. [4 ]
Harms, Kelly [1 ]
Nakamura, Mio [1 ]
机构
[1] Univ Michigan, Dept Dermatol, 1910 Taubman Ctr,1500 E Med Ctr Dr, Ann Arbor, MI 48109 USA
[2] Carle Illinois Coll Med, Urbana, IL USA
[3] Trinity Hlth, Livonia, MI USA
[4] Univ Michigan, Med Sch, Ann Arbor, MI USA
关键词
acanthosis nigricans; acrochordons; dyslipidemia; insulin resistance; metabolic syndrome; obesity; pediatric; skin tags; CUTANEOUS SIGN;
D O I
10.1111/pde.15639
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BackgroundAcrochordons or skin tags are common benign skin growths. Several studies explored the relationship between obesity and metabolic syndrome in adults but remains unexplored in children.MethodsThis was a single-center retrospective cohort study of outpatient dermatology patients between 1 January 2000 to 1 January 2021. Children under 18 years old diagnosed with acrochordons using diagnostic codes International Classification of Diseases, 10th Revision (ICD-10) L91.8 and 9th Revision (ICD-9) 701.8 were included. We collected patient demographics, past medical history, laboratory values, vital signs, and physical exam. Body mass index (BMI) was calculated and stratified into categories based on the Center for Disease Control's BMI-for-Age Growth Charts. Metabolic syndrome was diagnosed when three of the five criteria were met. Data were propensity-matched and compared with NHANES (National Health and Nutrition Examination Survey), which offered a generalizable sample to the US population.ResultsFifty-five patients under 18 years old with a diagnosis of acrochordons were mostly Caucasian (76%) and female (64%). The mean BMI was 27.3, with 49.5% categorized as obese and 20% as overweight. The mean age of diagnosis was 10.1 years. Acrochordon predominantly appeared in the axilla. In our cohort, three patients (5.5%) met the criteria for metabolic syndrome. The prevalence of obesity (42% vs. 21%), type 2 diabetes mellitus (4.8% vs. 0.6%), hyperlipidemia (8.1% vs. 0%), and hypertension (1.6% vs. 0%) was greater in our cohort compared with NHANES.ConclusionsLike the adult population, acrochordons may serve as marker for metabolic disease in the pediatric population.
引用
收藏
页码:660 / 666
页数:7
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