Treatment With Voclosporin and Anifrolumab in a Patient With Lupus Nephritis and Refractory Discoid Lupus Erythematosus: A Case Report and Literature Review

被引:2
作者
Karagenova, Ralina [1 ]
Vodusek, Ziga [2 ]
Krimins, Rebecca [3 ]
Krieger, Adam [2 ]
Timlin, Homa [2 ]
机构
[1] Univ Hawaii, John A Burns Sch Med, Rheumatol, Honolulu, HI USA
[2] Johns Hopkins Univ, Sch Med, Rheumatol, Baltimore, MD 21218 USA
[3] Johns Hopkins Univ, Sch Med, Radiol & Radiol Sci, Baltimore, MD USA
关键词
systemic lupus erythematosus; sle; anifrolumab; voclosporin; sle and lupus nephritis; lupus nephritis; discoid lupus erythematosus (dle); MORTALITY;
D O I
10.7759/cureus.55321
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Systemic lupus erythematosus (SLE) is a complex heterogeneous disease with multiple clinical manifestations. Recently, two medications, anifrolumab and voclosporin, have been approved for the treatment of adults with SLE and lupus nephritis (LN), respectively. We present the case of an elderly woman with LN and refractory discoid lupus erythematosus (DLE), who was treated successfully with a combination of voclosporin and anifrolumab without major infections.
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