A review of the treatment of bone tumours by hyperthermia using magnetic nanoparticles

被引:2
|
作者
Ehsani, Athena [1 ]
Mahale, Rayappa Shrinivas [2 ]
Shaygan, Shika [3 ]
Attaeyan, Ali [4 ]
Ghorbani, Atefeh [5 ]
Vasanth, Shamanth [2 ]
Sharath, P. C. [6 ]
Shahriari, Sheyda [7 ]
Asefnejad, Azadeh [1 ]
机构
[1] Islamic Azad Univ, Dept Biomed Engn, Sci & Res Branch, Tehran, Iran
[2] REVA Univ, Sch Mech Engn, Bengaluru, Karnataka, India
[3] Dept Pharm, Cyprus Hlth & Social Sci, TRNC Via Mersin 10, Guzelyurt, Turkey
[4] Islamic Azad Univ, Fac Biomech, Dept Biomed Engn, Najafabad Branch, Najafabad, Iran
[5] Islamic Azad Univ, Biotechnol Dept, Falavarjan Branch, Esfahan, Iran
[6] JAIN Deemed Univ, Dept Met & Mat Engn, Bangalore, Karnataka, India
[7] Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England
来源
JOURNAL OF NANOANALYSIS | 2022年 / 9卷 / 03期
关键词
Pharmaceuticals; application; Cancer Diagnosis; Magnetic Resonance Imaging; Magnetic Targeting; MECHANICAL-PROPERTIES; BIOACTIVITY; BEHAVIOR; COMPOSITE; TENSILE; STEEL;
D O I
10.22034/jna.2022.1944876.1278
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Cancer is a fatal disease that has long plagued and damaged people. In the last two decades, many researchers have been interested in the use of magnetic nanoparticles (MNPs) in medicine and pharmaceutical application particularly in the field of cancer diagnostics and treatment. The goal of this article is to provide an overview of MNPs as well as the principles of successful techniques for delivering these nanoparticles to cancer cells. According to an examination, there are two types of active and passive techniques for delivering MNPs to cancer cells. The targeted transfer of nanoparticles to the tumour happens in the active approach, which uses specific molecular ligands of tumour cells and irradiates an external magnetic field to the tumour area, whereas the passive method penetrates the tumour due to its permeability and nanoparticle retention. MNPs offer a variety of applications in biomedicine, including targeted medication delivery to tumours, magnetic resonance imaging, and cancer treatment with hyperthermia, due to their magnetic nature and capacity to carry pharmaceuticals. The use of MNPs in medicine has led to focus on the treatment of cancer. This review indicates that a reduction in the side effects and biological damage produced by chemotherapy in patients can be obtained using MNPs.
引用
收藏
页码:206 / 217
页数:12
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