Au-based bimetallic nanoparticles: current biomedical applications

被引：6
作者：
Arkhipova, Valeria I. [1 ]
Mochalova, Elizaveta N. [1 ,2 ,3 ]
Nikitin, Maxim P. [1 ,2 ]
机构：
[1] Sirius Univ Sci & Technol, Nanobiomed Div, 1 Olimpiyskiy Ave, Sirius 354340, Krasnodar Regio, Russia
[2] Moscow Ctr Adv Studies, Kulakova Str 20, Moscow 123592, Russia
[3] Moscow Inst Phys & Technol, 1A Kerchenskaya St, Moscow 117303, Russia
来源：
JOURNAL OF NANOPARTICLE RESEARCH | 2024年 / 26卷 / 09期
关键词：
Comparative review; Bimetallic gold nanoparticles; Antimicrobial; Anticancer; Biosensors; Bioimaging; Drug delivery; PLATINUM NANOPARTICLES; GOLD; SILVER; MECHANISMS; OXIDE;
D O I：
10.1007/s11051-024-06122-z
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The rapidly developing field of nanomedicine presents new challenges for researchers. Existing, clinically used preparations based on metal nanoparticles still have their limitations. Consequently, scientific attention is shifting from well-studied monometallic to bimetallic nanoparticles, which combine a synergistic combination of different metals in their composition. This review examines promising gold-containing bimetallic nanoparticles for use in biomedicine. Gold (Au) is the most popular initial choice in bimetallic nanoparticle (BNPs) composition due to its biocompatibility. As two metals combine in one particle, it becomes possible to reduce systemic toxicity and significantly increase the therapeutic effect. We provide a comprehensive assessment of the advantages and limitations of bimetallic nanoparticles and discuss potential solutions to the problems that have hindered their development.
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页数：18
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