Physiological Evidence and Therapeutic Outcomes of Vitamin D on Cardiovascular Diseases

被引：0
作者：
Zendehdel, Abolfazl [1 ]
Shakarami, Amir [2 ]
Moghadam, Ehsan Sekhavati [3 ]
机构：
[1] Univ Tehran Med Sci, Ziaeian Hosp, Dept Geriatr Med, Tehran, Iran
[2] Lorestan Univ Med Sci, Fac Med, Dept Cardiol, Khorramabad, Iran
[3] Univ Tehran Med Sci, Ziaeian Hosp, Dept Cardiol, Tehran, Iran
来源：
CURRENT CARDIOLOGY REVIEWS | 2024年 / 20卷 / 01期
关键词：
Vitamin D; cardiovascular; physiological functions; myocardial infarction; heart failure; hypertension; parathyroid hormone; RECEPTOR GENE POLYMORPHISM; RENIN-ANGIOTENSIN SYSTEM; D-DEFICIENCY; 1,25-DIHYDROXYVITAMIN D-3; 25-HYDROXYVITAMIN D; D SUPPLEMENTATION; D LEVEL; RISK; METAANALYSIS; ACTIVATION;
D O I：
10.2174/011573403X263417231107110618
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Vitamin D hormone is an important regulator of various physiological functions, and its deficiency is characterized by an imbalance in parathyroid hormone and calcium homeostasis. The role of vitamin D in cardiovascular physiology is well demonstrated in animal and human-based studies. In this context, hyperlipidemia, increased atherogenic plaques, cardiac inflammation, hypertension, myocarditis, myocardial infarction, and heart failure are some of the commonest known conditions connected with vitamin D deficiency. Supplementation of vitamin D is recommended to achieve normal serum vitamin D concentrations, nonetheless, in clinical trials often seen discrepancies concerning the supplementation effects and effectiveness. This review summarizes the data on the role of vitamin D in cardiovascular health along with some recent clinical findings regarding the effects of vitamin D supplementation.
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收藏
页码：91 / 100
页数：10
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