Disposable electrochemical sensors based on reduced graphene oxide/polyaniline/poly(alizarin red S)-modified integrated carbon electrodes for the detection of ciprofloxacin in milk

被引：4

作者：

Elancheziyan, Mari ^{[1
]}

Lee, Sooyeon ^{[1
]}

Yoon, Tae Hyun ^{[1
]}

Singh, Manisha ^{[1
]}

Lee, Dogyeong ^{[1
]}

Won, Keehoon ^{[1
]}

机构：

[1] Dongguk Univ Seoul, Coll Engn, Dept Chem & Biochem Engn, 30 Pildong ro 1 gil, Seoul 04620, South Korea

来源：

MICROCHIMICA ACTA | 2024年 / 191卷 / 09期

关键词：

Ciprofloxacin; Electrochemical sensor; Linear scan voltammetry; Electrochemically reduced graphene oxide; Polyaniline; Poly(alizarin red S); SCREEN-PRINTED ELECTRODES; SENSITIVE DETERMINATION; OXIDE-POLYANILINE; COMPOSITE FILM; BISPHENOL-A; NANOCOMPOSITE; CATECHOL; RESIDUES; ALIZARIN; ACID;

D O I：

10.1007/s00604-024-06578-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An electrochemical sensor based on an electroactive nanocomposite was designed for the first time consisting of electrochemically reduced graphene oxide (ERGO), polyaniline (PANI), and poly(alizarin red S) (PARS) for ciprofloxacin (CIPF) detection. The ERGO/PANI/PARS-modified screen-printed carbon electrode (SPCE) was constructed through a three-step electrochemical protocol and characterized using FTIR, UV-visible spectroscopy, FESEM, CV, LSV, and EIS. The new electrochemical CIPF sensor demonstrated a low detection limit of 0.0021 mu M, a broad linear range of 0.01 to 69.8 mu M, a high sensitivity of 5.09 mu A/mu M/cm(2), and reasonable selectivity and reproducibility. Moreover, the ERGO/PANI/PARS/SPCE was successfully utilized to determine CIPF in milk with good recoveries and relative standard deviation (< 5%), which were close to those with HPLC analysis.

引用

页数：12

共 64 条

[41] Fabrication of ciprofloxacin molecular imprinted polymer coating on a stainless steel wire as a selective solid-phase microextraction fiber for sensitive determination of fluoroquinolones in biological fluids and tablet formulation using HPLC-UV detection [J].