Total synthesis of natural alkaloids Schwarzinicines A-D

被引：3
作者：
Annapurna, K. [1 ,2 ]
Narsaiah, A. Venkat [1 ,2 ]
机构：
[1] CSIR Indian Inst Chem Technol, Fluoro Agrochem Dept, Organ Synth Lab, ,, Hyderabad 500007, Telangana, India
[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, India
来源：
TETRAHEDRON | 2024年 / 155卷
关键词：
Schwarzinicines; Vasorelaxant; Alkaloids; Henry reaction; Reductive amination; TITANIUM(IV) ISOPROPOXIDE; EFFICIENT;
D O I：
10.1016/j.tet.2024.133909
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Naturally occurring vasorelaxant alkaloids of 1,4-diarylbutanoidphenethylamines were synthesized successfully. Synthesis started from commercially available veratraldehyde, vanillin and piperonal. The important reactions involved in this synthesis are Corey -Fuchs, Eschweiler-Clarke, Henry reaction and lithium mediated carboncarbon bond formation.
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页数：6
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