Lemborexant-induced interstitial lung disease: A case report

被引：0

作者：

Nakahara, Satoshi ^{[1
]}

Ishii, Yumiko ^{[1
]}

Egashira, Reika ^{[1
]}

Tsubouchi, Kazuya ^{[1
]}

Kohno, Mikihiro ^{[2
]}

Takenaka, Tomoyoshi ^{[2
]}

Tanaka, Kentaro ^{[1
]}

Okamoto, Isamu ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med Sci, Dept Resp Med, Fukuoka, Fukuoka 8128581, Japan

[2] Kyushu Univ, Grad Sch Med Sci, Dept Surg & Sci, Fukuoka, Japan

来源：

RESPIROLOGY CASE REPORTS | 2024年 / 12卷 / 05期

关键词：

drug-induced interstitial lung disease; lemborexant; orexin receptor antagonists; type IV hypersensitivity reactions;

D O I：

10.1002/rcr2.1334

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

We report the first case of drug-induced interstitial lung disease attributed to lemborexant. A 66-year-old man reported to our hospital with the acute onset of cough and breathlessness with ground-glass opacity on radiological examination. Symptoms were identified after taking lemborexant for 2 consecutive days. The patient had undergone lemborexant treatment 2 years prior and had exhibited no symptoms at that time. The drug-induced lymphocyte stimulation test for lemborexant was positive. He showed rapid improvement upon treatment with steroid. With the rise in prescriptions of lemborexant for insomnia, lemborexant should be considered as a possible cause of drug-induced interstitial lung disease. We report the first case of drug-induced interstitial lung disease attributed to lemborexant. image

引用

页数：3

共 5 条

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