Synthesis of Novel Spirochromanone/1,2,3-Triazole Hybrid Heterocycles as Potential Antimicrobial Agents

被引：0

作者：

Raju, M. ^{[1
,2
]}

Hemasri, Y. ^{[1
]}

Rao, Y. Jayaprakash ^{[3
]}

机构：

[1] Osmania Univ, Dept Chem, Nizam Coll, Hyderabad 500001, India

[2] Govt Degree Coll, Alair 508101, India

[3] Osmania Univ, Univ Coll Sci Saifabad, Dept Chem, Hyderabad 500004, India

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2024年 / 94卷 / 06期

关键词：

spirochromanone; 1,2,3-triazole; Kabbe condensation; click reaction; TRIAZOLOTHIADIAZOLES;

D O I：

10.1134/S1070363224060203

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of new hybrid spirochromanone-1,2,3-triazole derivatives have been synthesized by employing a Cu(I)-catalyzed azide-alkyne [3+2] cycloaddition reaction. All compounds were characterized using H-1 NMR, C-13 NMR and HRMS methods. In addition, all synthesized compounds were tested in vitro for antimicrobial activity.

引用

页码：1436 / 1442

页数：7

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