Bacterial profiles detected in ventilator-associated pneumonia in Japan: A systematic review

被引：4

作者：

Moro, Hiroshi ^{[1
,6
]}

Aoki, Nobumasa ^{[1
]}

Matsumoto, Hiroyuki ^{[2
]}

Tone, Kazuya ^{[3
]}

Shuto, Hisayuki ^{[2
]}

Komiya, Kosaku ^{[2
,4
]}

Kikuchi, Toshiaki ^{[1
]}

Shime, Nobuaki ^{[5
]}

机构：

[1] Niigata Univ, Dept Resp Med & Infect Dis, Grad Sch Med & Dent Sci, 1-757 Asahimachi dori,Chuo ku, Niigata, Niigata 9528510, Japan

[2] Oita Univ, Resp Med & Infect Dis, Fac Med, 1-1 Idaigaoka, Yufu, Oita 8795593, Japan

[3] Jikei Univ, Kashiwa Hosp, Dept Resp Med, Sch Med, 1-163-1 Kashiwabuka, Kashiwa, Chiba 2778567, Japan

[4] Oita Univ, Res Ctr GLOBAL & LOCAL Infect Dis, Fac Med, 1-1 Idaigaoka, Yufu, Oita 8795593, Japan

[5] Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Emergency & Crit Care Med, 1-2-3 Kasumi,Minami ku, Hiroshima, Hiroshima 7348553, Japan

[6] Niigata Univ, Dept Resp Med & Infect Dis, Grad Sch Med & Dent Sci, 1Asahimachi dori,Chuo ku, Niigata 951, Japan

来源：

RESPIRATORY INVESTIGATION | 2024年 / 62卷 / 03期

关键词：

Ventilator -associated pneumonia; Pseudomonas aeruginosa; Methicillin-resistant Staphylococcus aureus; Systematic review; INTENSIVE-CARE-UNIT; GUIDELINES;

D O I：

10.1016/j.resinv.2024.01.012

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The primary objective of this study was to identify the predominant organisms associated with ventilatorassociated pneumonia (VAP) in Japan. Studies on VAP conducted in Japan were systematically reviewed, and seven studies with a total of 374 cases were included. The detection rate of each bacterium and multidrugresistant (MDR) pathogen was analyzed using the inverse variance method. Pseudomonas aeruginosa was identified as the predominant pathogen in 29.2 % of cases, followed by methicillin-resistant Staphylococcus aureus (MRSA) (12.0 %), and Klebsiella spp. (9.5 %). An integrated analysis revealed a detection rate of 57.8 % (95 % confidence interval: 48.7%-66.8 %) for MDR pathogens. This review highlights P. aeruginosa and MRSA as the predominant VAP-associated organisms in Japan, with a significant prevalence of MDR pathogens. This analysis provides valuable insights based on the regional distribution of bacteria detected in VAP, which is critical for selecting appropriate empirical therapy.

引用

页码：365 / 368

页数：4

共 16 条

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