Effects of Anthocyanins on Components of Metabolic Syndrome-A Review

被引:8
作者
Godyla-Jablonski, Michaela [1 ]
Raczkowska, Ewa [1 ]
Jodkowska, Anna [2 ]
Kucharska, Alicja Zofia [3 ]
Sozanski, Tomasz [4 ]
Bronkowska, Monika [5 ]
机构
[1] Wroclaw Univ Environm & Life Sci, Fac Biotechnol & Food Sci, Dept Human Nutr, Chelmonskiego 37, PL-51630 Wroclaw, Poland
[2] Wroclaw Med Univ, Dept Internal Med, Occupat Dis Hypertens & Clin Oncol, Borowska 213, PL-50556 Wroclaw, Poland
[3] Wroclaw Univ Environm & Life Sci, Dept Fruit Vegetable & Plant Nutraceut Technol, Chelmonskiego 37, PL-51630 Wroclaw, Poland
[4] Wroclaw Univ Sci & Technol, Dept Preclin Sci Pharmacol & Med Diag, Wybrzeze Wyspianskiego 27, PL-50370 Wroclaw, Poland
[5] Univ Opole, Inst Hlth Sci, Coll Salutis Humanae, Katowicka 68, PL-45060 Opole, Poland
关键词
anthocyanins; bioavailability; metabolic syndrome; obesity; dyslipidaemia; hypertension; oxidative stress; VACCINIUM-MYRTILLUS L; FRUITS CORNELIAN CHERRY; C-REACTIVE PROTEIN; OXIDATIVE STRESS; INSULIN-RESISTANCE; BLOOD-PRESSURE; DOUBLE-BLIND; ANTIOXIDANT PROPERTIES; CHEMICAL-COMPOSITION; CARDIOVASCULAR RISK;
D O I
10.3390/nu16081103
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Metabolic syndrome (MetS) is a significant health problem. The co-occurrence of obesity, carbohydrate metabolism disorders, hypertension and atherogenic dyslipidaemia is estimated to affect 20-30% of adults worldwide. Researchers are seeking solutions to prevent and treat the conditions related to MetS. Preventive medicine, which focuses on modifiable cardiovascular risk factors, including diet, plays a special role. A diet rich in fruits and vegetables has documented health benefits, mainly due to the polyphenolic compounds it contains. Anthocyanins represent a major group of polyphenols; they exhibit anti-atherosclerotic, antihypertensive, antithrombotic, anti-inflammatory and anticancer activities, as well as beneficial effects on endothelial function and oxidative stress. This review presents recent reports on the mechanisms involved in the protective effects of anthocyanins on the body, especially among people with MetS. It includes epidemiological data, in vivo and in vitro preclinical studies and clinical observational studies. Anthocyanins are effective, widely available compounds that can be used in both the prevention and treatment of MetS and its complications. Increased consumption of anthocyanin-rich foods may contribute to the maintenance of normal body weight and modulation of the lipid profile in adults. However, further investigation is needed to confirm the beneficial effects of anthocyanins on serum glucose levels, improvement in insulin sensitivity and reduction in systolic and diastolic blood pressure.
引用
收藏
页数:32
相关论文
共 246 条
[1]   Anthocyanins in berries exhibited anti-atherogenicity and antiplatelet activities in a metabolic syndrome population [J].
Aboonabi, Anahita ;
Meyer, Roselyn Rose ;
Gaiz, Almottesembellah ;
Singh, Indu .
NUTRITION RESEARCH, 2020, 76 :82-93
[2]   Anthocyanins reduce inflammation and improve glucose and lipid metabolism associated with inhibiting nuclear factor-kappaB activation and increasing PPAR-γ gene expression in metabolic syndrome subjects [J].
Aboonabi, Anahita ;
Aboonabi, Arta .
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 150 :30-39
[3]   Cytoprotective effects of berry anthocyanins against induced oxidative stress and inflammation in primary human diabetic aortic endothelial cells [J].
Aboonabi, Anahita ;
Singh, Indu ;
Meyer, Roselyn Rose .
CHEMICO-BIOLOGICAL INTERACTIONS, 2020, 317
[4]   Effects of blackberry (Morus nigra L.) consumption on serum concentration of lipoproteins, apo A-I, apo B, and high-sensitivity-C-reactive protein and blood pressure in dyslipidemic patients [J].
Aghababaee, Sahar Keshtkar ;
Vafa, Mohammadreza ;
Shidfar, Farzad ;
Tahavorgar, Atefeh ;
Gohari, Mahmoodreza ;
Katebi, Davod ;
Mohammadi, Vida .
JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2015, 20 (07) :684-691
[5]   Effects of Berry Anthocyanins on Cognitive Performance, Vascular Function and Cardiometabolic Risk Markers: A Systematic Review of Randomized Placebo-Controlled Intervention Studies in Humans [J].
Ahles, Sanne ;
Joris, Peter J. ;
Plat, Jogchum .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (12)
[6]   Anthocyanins Contents, Profiles, and Color Characteristics of Red Cabbage Extracts from Different Cultivars and Maturity Stages [J].
Ahmadiani, Neda ;
Robbins, Rebecca J. ;
Collins, Thomas M. ;
Giusti, M. Monica .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 62 (30) :7524-7531
[7]   Black carrot (Daucus carota L.), dietary and health promoting perspectives of its polyphenols: A review [J].
Akhtar, Saeed ;
Rauf, Abdur ;
Imran, Muhammad ;
Qamar, Muhammad ;
Riaz, Muhammad ;
Mubarak, Mohammad S. .
TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2017, 66 :36-47
[8]  
Akond A. S. M. G. M., 2011, American Journal of Food Technology, V6, P385
[9]   Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity [J].
Alberti, K. G. M. M. ;
Eckel, Robert H. ;
Grundy, Scott M. ;
Zimmet, Paul Z. ;
Cleeman, James I. ;
Donato, Karen A. ;
Fruchart, Jean-Charles ;
James, W. Philip T. ;
Loria, Catherine M. ;
Smith, Sidney C., Jr. .
CIRCULATION, 2009, 120 (16) :1640-1645
[10]  
Alberti KGMM, 1998, DIABETIC MED, V15, P539, DOI 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO