Disposable cerium oxide/graphene nanosheets based sensor for monitoring acebutolol in environmental samples and bio-fluids

被引：18

作者：

Selvi S.V. ^{[1
]}

Nataraj N. ^{[1
]}

Chen T.-W. ^{[1
,2
,3
]}

Chen S.-M. ^{[1
]}

Balu P. ^{[5
]}

Liu X. ^{[4
]}

机构：

[1] Electroanalysis and Bioelectrochemistry Lab, Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei

[2] Research and Development Center for Smart Textile Technology, National Taipei University of Technology, No.1, Section 3, Chung-Hsiao East Road, Taipei

[3] Department of Materials, Imperial College London, London

[4] Key Laboratory of Education Ministry for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing

[5] Department of Biotechnology, School of Life Science, Vels Institute of Science, Technology and Advanced Studies, Chennai, Tamilnadu

来源：

Journal of Environmental Chemical Engineering | 2022年 / 10卷 / 02期

关键词：

Conducting substrate; Environmental pollution; Human urine; Metal Oxide-Graphene nanosheets; River water;

D O I：

10.1016/j.jece.2022.107182

中图分类号：

学科分类号：

摘要：

The production and utilization of medicines strives to be an essential factor in the modern world in treatment, diagnosis and prevention. On the other hand, the medical discharge and the unmetabolized drugs all turns out into environmental polluting agents. The demand for detecting and solving these issues are essential. Herein, we report an electrochemical sensor for quantifying β-adrenoreceptor blocker acebutolol (ACT) in environmental and biological samples. Cerium oxide (CeO2) was implied with graphene nanosheets (GNS) as highly conducting material for electrochemically detecting ACT. The structural and morphological studies were studied and electrochemical analysis were also performed to efficiently study oxidation mechanism of ACT at CeO2/GNS interface. Electrochemical impedance spectroscopy (EIS) proved the higher conducting behavior of CeO2/GNS. Moreover, CeO2/GNS/SPCE holds higher surface area with more edge sites facilitating the electro-oxidation of ACT. The linear range of detecting ACT was in the range of 0.039 μM to 486.6 μM. The limit of detection was found to be 0.007 μM with the sensitivity about 27.3 μAμM−1cm−2. The real samples like river water and urine samples were utilized for real time detection of ACT. Thus, the fabricated electrode with more efficiency and higher conducting property will enhance the real time sensing of ACT in environmental and biological samples. © 2022 Elsevier Ltd

引用

共 36 条

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