Lighting the way: recent developments and applications in molecular optogenetics

被引：6
作者：
Armbruster, Anja [1 ,2 ,3 ]
Mohamed, Asim M. E. [1 ]
Phan, Hoang T. [1 ]
Weber, Wilfried [1 ,2 ,4 ]
机构：
[1] INM Leibniz Inst New Mat, Campus D2 2, D-66123 Saarbrucken, Germany
[2] Univ Freiburg, CIBSS Ctr Integrat Biol Signalling Studies, Schanzlestr 18, D-79104 Freiburg, Germany
[3] Univ Freiburg, Fac Biol, Schanzlestr 1, D-79104 Freiburg, Germany
[4] Saarland Univ, Dept Mat Sci & Engn, Campus D2 2, D-66123 Saarbrucken, Germany
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2024年 / 87卷
基金：
欧洲研究理事会;
关键词：
D O I：
10.1016/j.copbio.2024.103126
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Molecular optogenetics utilizes genetically encoded, lightresponsive protein switches to control the function of molecular processes. Over the last two years, there have been notable advances in the development of novel optogenetic switches, their utilization in elucidating intricate signaling pathways, and their progress toward practical applications in biotechnological processes, material sciences, and therapeutic applications. In this review, we discuss these areas, offer insights into recent developments, and contemplate future directions.
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页数：10
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