Photoinactivation of Escherichia coli and Staphylococcus aureus using Porphyrin-CuInS2/ZnS quantum dot conjugates immobilized on Mesoporous Silica

被引：4

作者：

Ndlovu, Knowledge Siyabonga ^{[1
]}

Chokoe, Khomotso ^{[2
]}

Masebe, Tracy ^{[2
]}

Sekhosana, Kutloano Edward ^{[1
]}

Moloto, Makwena Justice ^{[1
]}

Managa, Muthumuni ^{[1
]}

机构：

[1] Univ South Africa, Inst Nanotechnol & Water Sustainabil iNanoWS, Coll Sci Engn & Technol CSET, ZA-1710 Johannesburg, South Africa

[2] Univ South Africa, Coll Agr & Environm Sci CAES, Dept Life & Consumer Sci, ZA-1710 Johannesburg, South Africa

来源：

CHEMICAL PAPERS | 2024年 / 78卷 / 08期

关键词：

E; coli; S; aureus; Porphyrin; Quantum dots; Antimicrobial photodynamic inactivation; Mesoporous silica; PHOTODYNAMIC INACTIVATION; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; CATIONIC PORPHYRINS; IN-VITRO; PHOTOSENSITIZERS; BACTERIA; SINGLET; GROWTH;

D O I：

10.1007/s11696-024-03447-w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Bacterial pathogens remain major contributors to illnesses as they have developed several resistance mechanisms against standard treatments. Innovative porphyrin-quantum dots conjugated materials have great potential in addressing the limitations in the current disinfection methods. The antimicrobial activity of metal-free and In(III) derivative of 4-(15-(4-boronophenyl)-10,20-diphenylporphyrin-5-yl)benzoic acid conjugated to CuInS2/ZnS quantum dots is investigated in this study at laboratory-scale experiments under controllable conditions. The conjugate was also immobilized on mesoporous silica for recovery and reusability purposes. Findings of the study were driven by antimicrobial photodynamic inactivation (aPDI) in the presence of a porphyrin and quantum dots. POR(In)-CIS/ZnS QDs-Silica was the best performing conjugate with a singlet quantum yield (Phi(Delta)) of 0.72 and a log reduction of 9.38 and 9.76 against Escherichia coli and S. aureus, respectively.

引用

页码：4991 / 5004

页数：14

共 54 条

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