Mechanism of Peptide Self-assembly and Its Study in Biomedicine

被引:6
作者
Yang, Xinyue [1 ]
Ma, Li [1 ]
Lu, Kui [1 ]
Zhao, Dongxin [1 ]
机构
[1] Henan Univ Technol, Sch Chem & Chem Engn, Locus St,High Tech Ind Dev Zone, Zhengzhou 450001, Henan, Peoples R China
基金
中国国家自然科学基金;
关键词
Peptides; Drug Delivery; Cancer Therapy; Nanomaterials; Hydrogel; AMPHIPHILIC PEPTIDES; HYDROGELS; DELIVERY; NANOTUBES;
D O I
10.1007/s10930-024-10200-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The development of peptide-based materials is one of the most challenging aspects of biomaterials research in recent years. The assembly of peptides is mainly controlled by forces such as hydrogen bonding, hydrophobic interaction, electrostatic interaction, and pi-pi accumulation. Peptides have unique advantages such as simple structure, easy synthesis, good biocompatibility, non-toxicity, easy modification, etc. These factors make peptides turn into ideal biomedical materials, and they have a broad application prospect in biomedical materials, and thus have received wide attention. In this review, the mechanism and classification of peptide self-assembly and its applications in biomedicine and hydrogels were introduced.
引用
收藏
页码:464 / 476
页数:13
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