Dual threshold input receiver FPGA-only signal digitization method for time-of-flight positron emission tomography

被引:3
作者
Ko, Guen Bae [1 ,2 ]
Lee, Jae Sung [1 ,2 ,3 ,4 ]
机构
[1] Brightonix Imaging Inc, Seoul 04782, South Korea
[2] Seoul Natl Univ, Inst Radiat Med, Med Res Ctr, Seoul 03080, South Korea
[3] Seoul Natl Univ, Coll Med, Dept Nucl Med, Seoul 03080, South Korea
[4] Seoul Natl Univ, Coll Engn, Interdisciplinary Program Bioengn, Seoul 03080, South Korea
关键词
Positron emission tomography; Field-programmable gate array; Silicon photomultiplier; Time-to-digital converter; Time-over-threshold; PET; PET/MRI;
D O I
10.1007/s13534-024-00380-5
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
As silicon photomultiplier (SiPM)-based time-of-flight (TOF) positron emission tomography (PET) becomes popular, the need for sophisticated PET data acquisition (DAQ) systems is increasing. One promising solution to this challenge is the adoption of a field-programmable gate array (FPGA)-only signal digitization method. In this paper, we propose a new approach to efficiently implement an FPGA-only digitizer. We configured the input/output (IO) port of the FPGA to function as a dual-threshold voltage comparator through the use of simple passive circuitry and heterogeneous IO standards. This configuration overcomes the limitations of existing methods by allowing different threshold voltages for adjacent IO pins, effectively reducing routing complexity and lowering manufacturing costs. An FPGA-only digitizer was implemented by integrating the dual-threshold voltage comparator and FPGA-based time-to-digital converter. By combining the dual-threshold time-over-threshold (TOT) method and curve fitting, precise energy information could be obtained. The performance of the FPGA-only digitizer was assessed using a detector setup comprising a 3 x 3 x 20 mm3 LYSO scintillation crystal and a single pixel SiPM. Using the configured evaluation setup, an energy resolution of 12.5% and a time resolution of 146 +/- 9 ps were achieved for a 20 mm scintillation crystal. The dual-threshold TOT implemented using the proposed method showed consistent linearity across an energy range of 100 keV to 600 keV. The proposed method is well-suited for the development of cost-effective DAQ systems in highly integrated TOF PET systems.
引用
收藏
页码:847 / 858
页数:12
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