A Miniaturized, Low-Frequency Magnetoelectric Wireless Power Transfer System for Powering Biomedical Implants

被引:12
作者
Mukherjee, Dibyajyoti [1 ]
Rainu, Simran Kaur [2 ]
Singh, Neetu [2 ,3 ]
Mallick, Dhiman [1 ]
机构
[1] Indian Inst Technol Delhi IIT Delhi, Dept Elect Engn, New Delhi 110016, India
[2] Indian Inst Technol Delhi IIT Delhi, Ctr Biomed Engn, New Delhi 110016, India
[3] All India Inst Med Sci AIIMS, Biomed Engn Unit, New Delhi 110029, India
关键词
Biocompatabilty; implantable medical device (IMD); magnetoelectric (ME); power management circuit (PMC); wireless power transfer (WPT); MANAGEMENT CIRCUIT; ANTENNAS;
D O I
10.1109/TBCAS.2023.3336598
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This work experimentally demonstrates the operation of a miniaturized magnetoelectric (ME) wireless power transfer (WPT) system by incorporating a ME transducer and a suitable interface power management circuit (PMC) for potentially powering implantable medical devices (IMD) wirelessly. A ME heterostructure is micromachined to obtain desired device dimensions of 3.5 x 5 mm(2 )and to restrict the operating frequency at a clinically approved frequency of 50 kHz. The proposed work also aims to address the trade-off between the device miniaturization, power attenuation and limiting the specific absorption rate (SAR) in the human tissue. By limiting the operating frequency to 50 kHz, the SAR is reduced to less than 1 mu W/kg. The fabricated device is characterized with low-intensity AC magnetic field up to 40 mu T without using any DC bias, resulting in 0.4 V output voltage and 6.6 mu W power across 8 k Omega load. Alignment misorientation between the Tx and Rx is studied for in-plane and out-of-plane angular rotations to confirm the device's reliability against angular misalignment. By eliminating the bulky biasing magnets, the proposed device achieves a significant size reduction compared to the previously reported works. In addition, a self-powered interface PMC is incorporated with the ME system. The PMC generates 3.5 V regulated DC voltage from the input AC voltage range 0.7 V to 3.3 V. The PMC is fabricated on a 2-layered PCB and the over all ME WPT system consumes 12 x 12 mm(2) area. The overall PMC has intrinsic current consumption less than 550 nA with peak power conversion efficiency higher than 85%. The in vitro cytotoxicity analysis in the human hepatic cell line WRL-68 confirmed the biocompatibility of the Parylene-C encapsulated ME device for up to 7 days, suggesting its potential use in implantable electronic devices for biomedical and clinical applications.
引用
收藏
页码:438 / 450
页数:13
相关论文
共 57 条
[1]   An Inductive Link-Based Wireless Power Transfer System for Biomedical Applications [J].
Adeeb, M. ;
Islam, A. ;
Haider, M. ;
Tulip, F. ;
Ericson, M. ;
Islam, S. .
ACTIVE AND PASSIVE ELECTRONIC COMPONENTS, 2012, 2012
[2]   A Micro Inertial Energy Harvesting Platform With Self-Supplied Power Management Circuit for Autonomous Wireless Sensor Nodes [J].
Aktakka, Ethem Erkan ;
Najafi, Khalil .
IEEE JOURNAL OF SOLID-STATE CIRCUITS, 2014, 49 (09) :2017-2029
[3]  
[Anonymous], 2010, Standard 60601-2-33 Ed 3.0
[4]  
[Anonymous], GOVERNING BODY 309 S
[5]  
[Anonymous], 2016, ADP5092 Ultralow Power Energy Harvester PMU With MPPT and Charge Management Datasheet and Product, Analog Devices
[6]   Miniaturised Wireless Power Transfer Systems for Neurostimulation: A Review [J].
Barbruni, Gian Luca ;
Ros, Paolo Motto ;
Demarchi, Danilo ;
Carrara, Sandro ;
Ghezzi, Diego .
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2020, 14 (06) :1160-1178
[7]   A review of acoustic power transfer for biomedical implants [J].
Basaeri, Hamid ;
Christensen, David B. ;
Roundy, Shad .
SMART MATERIALS AND STRUCTURES, 2016, 25 (12)
[8]   Comparisons of computed mobile phone induced SAR in the SAM phantom to that in anatomically correct models of the human head [J].
Beard, Brian B. ;
Kainz, Wolfgang ;
Onishi, Teruo ;
Iyama, Takahiro ;
Watanabe, Soichi ;
Fujiwara, Osamu ;
Wang, Jianqing ;
Bit-Babik, Giorgi ;
Faraone, Antonio ;
Wiart, Joe ;
Christ, Andreas ;
Kuster, Niels ;
Lee, Ae-Kyoung ;
Kroeze, Hugo ;
Siegbahn, Martin ;
Keshvari, Jafar ;
Abrishamkar, Houman ;
Simon, Winfried ;
Manteuffel, Dirk ;
Nikoloski, Neviana .
IEEE TRANSACTIONS ON ELECTROMAGNETIC COMPATIBILITY, 2006, 48 (02) :397-407
[9]   A Tutorial on the Receiving and Scattering Properties of Antennas [J].
Best, Steven R. ;
Kaanta, Bradley C. .
IEEE ANTENNAS AND PROPAGATION MAGAZINE, 2009, 51 (05) :26-37
[10]   A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves [J].
Chen, Joshua C. ;
Kan, Peter ;
Yu, Zhanghao ;
Alrashdan, Fatima ;
Garcia, Roberto ;
Singer, Amanda ;
Lai, C. S. Edwin ;
Avants, Ben ;
Crosby, Scott ;
Li, Zhongxi ;
Wang, Boshuo ;
Felicella, Michelle M. ;
Robledo, Ariadna ;
Peterchev, Angel, V ;
Goetz, Stefan M. ;
Hartgerink, Jeffrey D. ;
Sheth, Sunil A. ;
Yang, Kaiyuan ;
Robinson, Jacob T. .
NATURE BIOMEDICAL ENGINEERING, 2022, 6 (06) :706-716