Regulation of fatty acid synthase on tumor and progress in the development of related therapies

被引：0
作者：
Bai Rilan
Cui Jiuwei
机构：
[1] CancerCenter,theFirstHospitalofJilinUniversity,Changchun,Jilin,China
来源：
中华医学杂志英文版 | 2024年 / 137卷 / 16期
关键词：
Neoplasm; Fatty acid synthase; Fatty acid synthase inhibitor; Immune regulation;
D O I：
暂无
中图分类号：
R730.5 [肿瘤治疗学];
学科分类号：
摘要：
Fatty acid synthase (FASN) is an essential molecule in lipid metabolic pathways, which are crucial for cancer-related studies. Recent studies have focused on a comprehensive understanding of the novel and important regulatory effects of FASN on malignant biological behavior and immune-cell infiltration, which are closely related to tumor occurrence and development, immune escape, and immune response. FASN-targeting antitumor treatment strategies are being developed. Therefore, in this review, we focused on the effects of FASN on tumor and immune-cell infiltration and reviewed the progress of related antitumor therapy development.
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