CrystalStructureandInteractionwithDNAof[Ni（phen）(mal)（H2O）2]·3H2O

A new complex [Ni(phen)(mal)(H2O)2]·3H2O (phen = 1,10-phenanthroline, mal2-= malonic acid) has been synthesized by the reaction of nickel nitrate, phen and malonic acid. EA, IR spectra and X-ray single-crystal diffraction were carried out to determine the composition and crystal structure of the title complex. Crystal data: monoclinic system, space group P2/c, a = 8.937(3), b = 12.163(5), c = 9.725(3) , β = 119.36°, C15H19N2O9Ni, Mr = 430.03, Z = 2, F(000) = 446, V = 921.3 3, Dc = 1.550 g/cm3, μ = 1.104 mm-1, –10≤h≤10, –12≤k≤14, –11≤l≤7, R = 0.0261 and wR = 0.0609 for 4376 (Rint = 0.0203) independent reflections and 1631 observed ones (I > 2σ(I)). Ni(Ⅱ) exhibits an octahedral coordination geometry, with hydrogen bonds and π-π interactions stabilizing the whole structure. UV spectrum of the complex interacting with protamine DNA indicates that the title compound interacts with DNA via insertion mode with bonding constant Kb of 1.11×104.