Synthesis, Characterization and Antimicrobial Study of a New Schiff Base Paeonol-phenylpropanolamine

被引：5

作者：

许同桃 ^{[1
]}

许兴友 ^{[1
]}

高健 ^{[2
]}

刘兰蕾 ^{[1
]}

倪帅帅 ^{[1
]}

陆路德 ^{[3
]}

杨绪杰 ^{[3
]}

机构：

[1] Department of Chemical Engineering, Huaihai Institute of Technology

[2] Department of Chemical Engineering, Lianyungang Technical College

[3] Materials Chemistry Laboratory, Nanjing University of Science &

来源：

结构化学 | 2006年 / 12期

关键词：

D O I：

暂无

中图分类号：

TQ455 [杀菌剂];

学科分类号：

摘要：

A novel Schiff base compound was synthesized by the reaction of paeonol and phenylpropanolamine in absolute methanol. It was characterized by elemental analyses, IR, 1H NMR and X-ray single-crystal diffraction. The compound crystallizes in the triclinic system, space group P1, with a = 6.4075(11), b = 10.2821(18), c = 12.573(2) ·, α = 92.606(3), β = 100.980(3), γ = 90.994(3)°, V = 812.1(2) ·3, Mr = 299.36, Z = 2, F(000) = 320, Dc = 1.224 g/cm3, T = 293(2) K, μ = 0.083 mm-1 and λ = 0.71073 ·, the final R = 0.0555 and wR = 0.1619 for 2442 observed reflections with I > 2σ(I). The compound was valued for its antimicrobial activity against bacterial strands using the agar diffusion method. It is found to be active against Candida albicans and Staphylococcus aureus.

引用

页码：1502 / 1506

页数：5