Microwave Assistant Synthesis,Crystal Structure and Biological Activity of 1-(2-Fluorobenzyl)-3-methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one

被引：0

作者：

雷超 ^{[1
]}

申屠超 ^{[1
]}

机构：

[1] College of Biology and Environmental Engineering,Zhejiang Shuren University

来源：

结构化学 | 2015年 / 34卷 / 11期

关键词：

1,2,4-triazole; synthesis; crystal structure; fungicidal activities;

D O I：

暂无

中图分类号：

O626 [杂环化合物];

学科分类号：

070303 ; 081704 ;

摘要：

The title compound 1-(2-fluorobenzyl)-3-methoxy-4-methyl-1H-1,2,4-triazol-5(4H)-one(C11H12FN3O2) was synthesized,and its structure was confirmed by 1H NMR,IR,MS,elemental analysis and X-ray diffraction.It crystallizes in the monoclinic system,space group P1 with a=6.919(3),b=8.525(4),c=9.811(4) ?,α=84.22(2),β=71.028(19),γ=86.10(2)°,Dc=1.448 g/cm3,Z=2,V=544.2(4) ?3,F(000)=248,the final R=0.0379 and w R=0.0913 for 1709 observed reflections with I > 2σ(I).The preliminary biological test shows that the title compound shows weak inhibitory activities against Phytophthora infestans,Botrytis cinerea,Corynespora cassiicola,Rhizoctonia solani and Pythium ultimum.

引用

页码：1659 / 1664

页数：6

共 19 条

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