Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy

被引：0

作者：

Lihong Liu ^{[1
]}

Birong Zheng ^{[1
]}

Manhui Luo ^{[1
]}

Jie Du ^{[1
]}

Fang Yang ^{[2
]}

Chuanxin Huang ^{[2
]}

Zengyi Ma ^{[3
]}

Chunmei Li ^{[1
]}

Deyin Guo ^{[1
]}

Hong Peng ^{[1
]}

机构：

[1] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University

[2] Shanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine

[3] Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan

来源：

Protein & Cell | 2023年 / 14卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

<正>Dear Editor,Ferroptosis is a newly discovered form of regulated cell death characterized by increased intracellular iron accumulation and subsequent lipid peroxidation (Dixon et al., 2012). Studies have revealed that ferroptosis plays an important role in multiple physiological and pathological processes including degenerative diseases, carcinogenesis, and cancer immunotherapy (Hassannia et al., 2019, Wang et al., 2019).

引用

页码：230 / 254

页数：25

共 50 条

[41] TRIM72-mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells
Wang, Cheng-Cheng
Peng, Hong
Wang, Zi
Yang, Jiao
Hu, Rong-Gui
Li, Chuan-Yin
Geng, Wu-Jun
MILITARY MEDICAL RESEARCH, 2022, 9 (01)
[42] p62/SQSTM1, a Key Autophagy Mediator, Is Regulated in Pancreatitis Through mTOR-Mediated Pathways
Pimienta, Michael
Lotshaw, Ethan
Elperin, Jason
Malla, Sudarshan
Ohmuraya, Masaki
Mareninova, Olga
Gukovskaya, Anna
Gukovsky, Ilya
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2016, 111 : S14 - S14
[43] Proteasome and p62/SQSTM1 are involved in methylmercury toxicity mitigation in mouse embryonic fibroblast cells
Takanezawa, Yasukazu
Nakamura, Ryosuke
Ohshiro, Yuka
Uraguchi, Shimpei
Kiyono, Masako
JOURNAL OF TOXICOLOGICAL SCIENCES, 2023, 48 (06): : 355 - 361
[44] An inhibition of p62/SQSTM1 caused autophagic cell death of several human carcinoma cells
Nihira, Kaito
Miki, Yasuhiro
Ono, Katsuhiko
Suzuki, Takashi
Sasano, Hironobu
CANCER SCIENCE, 2014, 105 (05) : 568 - 575
[45] TRIM72-mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells
Cheng-Cheng Wang
Hong Peng
Zi Wang
Jiao Yang
Rong-Gui Hu
Chuan-Yin Li
Wu-Jun Geng
Military Medical Research, 2023, 10 (04) : 559 - 562
[46] TRIM72-mediated degradation of the short form of p62/SQSTM1 rheostatically controls selective autophagy in human cells
Cheng-Cheng Wang
Hong Peng
Zi Wang
Jiao Yang
Rong-Gui Hu
Chuan-Yin Li
Wu-Jun Geng
Military Medical Research, 9
[47] ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human ARPE-19 cells
Amadio, M.
ACTA OPHTHALMOLOGICA, 2013, 91
[48] IL-1β Induces p62/SQSTM1 and Represses Androgen Receptor Expression in Prostate Cancer Cells
Chang, M. A.
Patel, V.
Gwede, M.
Morgado, M.
Tomasevich, K.
Fong, E. L.
Farach-Carson, M. C.
Delk, Nikki A.
JOURNAL OF CELLULAR BIOCHEMISTRY, 2014, 115 (12) : 2188 - 2197
[49] SQSTM1/p62 (sequestosome 1) senses cellular ubiquitin stress through E2-mediated ubiquitination
Yang, Jiao
Peng, Hong
Xu, Yumin
Xie, Xiaoduo
Hu, Ronggui
AUTOPHAGY, 2018, 14 (06) : 1072 - 1073
[50] LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I
Xian, Huifang
Yang, Shuai
Jin, Shouheng
Zhang, Yuxia
Cui, Jun
AUTOPHAGY, 2020, 16 (03) : 408 - 418

← 1 2 3 4 5 →