Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy

被引：0

作者：

Lihong Liu ^{[1
]}

Birong Zheng ^{[1
]}

Manhui Luo ^{[1
]}

Jie Du ^{[1
]}

Fang Yang ^{[2
]}

Chuanxin Huang ^{[2
]}

Zengyi Ma ^{[3
]}

Chunmei Li ^{[1
]}

Deyin Guo ^{[1
]}

Hong Peng ^{[1
]}

机构：

[1] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University

[2] Shanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine

[3] Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan

来源：

Protein & Cell | 2023年 / 14卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

<正>Dear Editor,Ferroptosis is a newly discovered form of regulated cell death characterized by increased intracellular iron accumulation and subsequent lipid peroxidation (Dixon et al., 2012). Studies have revealed that ferroptosis plays an important role in multiple physiological and pathological processes including degenerative diseases, carcinogenesis, and cancer immunotherapy (Hassannia et al., 2019, Wang et al., 2019).

引用

页码：230 / 254

页数：25

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