Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy

被引：0

作者：

Lihong Liu ^{[1
]}

Birong Zheng ^{[1
]}

Manhui Luo ^{[1
]}

Jie Du ^{[1
]}

Fang Yang ^{[2
]}

Chuanxin Huang ^{[2
]}

Zengyi Ma ^{[3
]}

Chunmei Li ^{[1
]}

Deyin Guo ^{[1
]}

Hong Peng ^{[1
]}

机构：

[1] MOE Key Laboratory of Tropical Disease Control, Centre for Infection and Immunity Study (CIIS), School of Medicine, Sun Yat-sen University

[2] Shanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine

[3] Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan

来源：

Protein & Cell | 2023年 / 14卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

<正>Dear Editor,Ferroptosis is a newly discovered form of regulated cell death characterized by increased intracellular iron accumulation and subsequent lipid peroxidation (Dixon et al., 2012). Studies have revealed that ferroptosis plays an important role in multiple physiological and pathological processes including degenerative diseases, carcinogenesis, and cancer immunotherapy (Hassannia et al., 2019, Wang et al., 2019).

引用

页码：230 / 254

页数：25

共 50 条

[1] Suppression of USP8 sensitizes cells to ferroptosis via SQSTM1/p62-mediated ferritinophagy
Liu, Lihong
Zheng, Birong
Luo, Manhui
Du, Jie
Yang, Fang
Huang, Chuanxin
Ma, Zengyi
Li, Chunmei
Guo, Deyin
Peng, Hong
PROTEIN & CELL, 2023, 14 (03) : 230 - 234
[2] S-acylation regulates SQSTM1/p62-mediated selective autophagy
Huang, Xue
Liu, Lu
Yao, Jia
Lin, Changhai
Xiang, Tingxiu
Yang, Aimin
AUTOPHAGY, 2024, 20 (06) : 1467 - 1469
[3] SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity
Demishtein, Alik
Fraiberg, Milana
Berko, Dikla
Tirosh, Boaz
Elazar, Zvulun
Navon, Ami
AUTOPHAGY, 2017, 13 (10) : 1697 - 1708
[4] The ubiquitin-specific protease USP8 directly deubiquitinates SQSTM1/p62 to suppress its autophagic activity
Peng, Hong
Yang, Fang
Hu, Qianwen
Sun, Jian
Peng, Cheng
Zhao, Yao
Huang, Chuanxin
AUTOPHAGY, 2020, 16 (04) : 698 - 708
[5] Glycyrol attenuates colon injury via promotion of SQSTM1/p62 ubiquitination and autophagy by inhibiting the ubiquitin-specific protease USP8
Lu, Shangyun
Xu, Jiali
Xu, Yang
Liu, Yang
Shi, Dongxing
Wang, Jia
Qiu, Fubin
JOURNAL OF FUNCTIONAL FOODS, 2023, 103
[6] Chemical modulation of SQSTM1/p62-mediated xenophagy that targets a broad range of pathogenic bacteria
Lee, Yoon Jee
Kim, Jin Kyung
Jung, Chan Hoon
Kim, Young Jae
Jung, Eui Jung
Lee, Su Hyun
Choi, Ha Rim
Son, Yeon Sung
Shim, Sang Mi
Jeon, Sang Min
Choe, Jin Ho
Lee, Sang-Hee
Whang, Jake
Sohn, Kyung-Cheol
Hur, Gang Min
Kim, Hyun Tae
Yeom, Jinki
Jo, Eun-Kyeong
Kwon, Yong Tae
AUTOPHAGY, 2022, 18 (12) : 2926 - 2945
[7] Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation
Zhou, Lingli
He, Xing
Wang, Liqiu
Wei, Ping
Cai, Zhe
Zhang, Song
Jin, Shouheng
Zeng, Huasong
Cui, Jun
CELL DEATH AND DIFFERENTIATION, 2022, 29 (08): : 1541 - 1551
[8] Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation
Lingli Zhou
Xing He
Liqiu Wang
Ping Wei
Zhe Cai
Song Zhang
Shouheng Jin
Huasong Zeng
Jun Cui
Cell Death & Differentiation, 2022, 29 : 1541 - 1551
[9] FBXO45 restricts HIV-1 replication by inducing SQSTM1/p62-mediated autophagic degradation of Tat
Xu, Mingxiu
Hu, Haobo
Yang, Weijing
Zhang, Jiaxiang
Wang, Hong
Zhang, Wenyan
Huan, Chen
JOURNAL OF VIROLOGY, 2025,
[10] α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy
Xu, Qianhui
Wang, Huilan
Yang, Ruonan
Tao, Youqi
Wang, Ziying
Zhang, Shengnan
Sun, Bo
Li, Dan
Lu, Boxun
Liu, Cong
CELL RESEARCH, 2025, 35 (01) : 72 - 75

← 1 2 3 4 5 →