Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques

被引：0
|
作者：
LI Lin1
2 Xi Yuan Hospital
机构：
来源：
ChineseScienceBulletin | 2007年 / 22期
关键词：
metabonomics; NMR; Qi deficiency and blood stasis syndrome; urine;
D O I：
暂无
中图分类号：
R255 [一般病证]; R310 [];
学科分类号：
1001 ; 100506 ;
摘要：
Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate,creatinine,2-oxoglutarate(2-OG) ,citrate,taurine,trimethylamine-N-oxide(TMAO) ,succinate and hippurate in the urine of the rats with Qi deficiency and blood stasis syndrome have been changed. These results have provided evidence for understanding the mechanism and the therapy of Qi defi-ciency and blood stasis syndrome.
引用
收藏
页码：3068 / 3073
页数：6
相关论文
共 50 条
  • [1] Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome based on NMR techniques
    Li Lin
    Wang JianNong
    Ren JianXun
    Xiang JunFeng
    Tang Yalin
    Liu JianXun
    Han Ding
    CHINESE SCIENCE BULLETIN, 2007, 52 (22): : 3068 - 3073
  • [2] NMR-based Metabonomics Studies on Serum and Urine of Yang-deficiency Constitution
    Li Ying-Shuai
    Wang Qi
    Yuan Zhuo-Jun
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2011, 32 (11): : 2521 - 2527
  • [3] Huangqi-Honghua combination and its main components ameliorate cerebral infarction with Qi deficiency and blood stasis syndrome by antioxidant action in rats
    Cao, Jinyi
    Chen, Zhengyu
    Zhu, Yanrong
    Li, Yuwen
    Guo, Chao
    Gao, Kai
    Chen, Lei
    Shi, Xiaopeng
    Zhang, Xiaofang
    Yang, Zhifu
    Wen, Aidong
    JOURNAL OF ETHNOPHARMACOLOGY, 2014, 155 (02) : 1053 - 1060
  • [4] Analysis of the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model using 1H-NMR-based metabonomics
    Zheng, Xiao-fen
    Tian, Jun-sheng
    Liu, Peng
    Xing, Jie
    Qin, Xue-mei
    JOURNAL OF ETHNOPHARMACOLOGY, 2014, 151 (02) : 912 - 920
  • [5] A metabonomics and lipidomics based network pharmacology study of qi-tonifying effects of honey-processed Astragalus on spleen qi deficiency rats
    Huang, Li
    Ye, Mingzhu
    Wu, Jiacai
    Liu, Wuping
    Chen, Hongyuan
    Rui, Wen
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 1146
  • [6] Study on correspondence between prescription and syndrome and the essence of phlegm and blood stasis syndrome in coronary heart disease based on metabonomics
    Lu Xiao-yan
    Xu Hao
    Li Geng
    Zhao Tie
    CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2014, 20 (01) : 68 - 71
  • [7] Study on correspondence between prescription and syndrome and the essence of phlegm and blood stasis syndrome in coronary heart disease based on metabonomics
    Xiao-yan Lu
    Hao Xu
    Geng Li
    Tie Zhao
    Chinese Journal of Integrative Medicine, 2014, 20 : 68 - 71
  • [8] Metabolic Signatures of Lung Cancer in Biofluids: NMR-Based Metabonomics of Urine
    Carrola, Joana
    Rocha, Claudia M.
    Barros, Antonio S.
    Gil, Ana M.
    Goodfellow, Brian J.
    Carreira, Isabel M.
    Bernardo, Joao
    Gomes, Ana
    Sousa, Vitor
    Carvalho, Lina
    Duarte, Iola F.
    JOURNAL OF PROTEOME RESEARCH, 2011, 10 (01) : 221 - 230
  • [9] Study on Correspondence between Prescription and Syndrome and the Essence of Phlegm and Blood Stasis Syndrome in Coronary Heart Disease Based on Metabonomics
    鹿小燕
    徐浩
    李耿
    赵铁
    Chinese Journal of Integrative Medicine, 2014, (01) : 68 - 71
  • [10] NMR Based Metabolomics Comparison of Different Blood Sampling Techniques in Awake and Anesthetized Rats
    Du, Hongying
    Li, Shuang
    Zhang, Yingfeng
    Guo, Huiling
    Wu, Liang
    Liu, Huili
    Manyande, Anne
    Xu, Fuqiang
    Wang, Jie
    MOLECULES, 2019, 24 (14):
12345