Prognostic value of ΔSYNTAX% score in octogenarians undergoing percutaneous coronary intervention

OBJECTIVES To verify whether incomplete revascularisation(IR), quantified using the rSYNTAX(Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score and ΔSYNTAX% score, could predict short-(in-hospital mortality) and long-term outcomes(12-month mortality) in octogenarians undergoing percutaneous coronary intervention(PCI).METHODS & RESULTS A retrospective analysis of 665 consecutive octogenarian patients presenting for PCI to a UK centre was performed. The baseline SYNTAX and rSYNTAX scores were assessed from angiographic images. ΔSYNTAX% score was calculated(ΔSYNTAX% =((SYNTAX – rSYNTAX)/SYNTAX) × 100%)) to measure the relative completeness of revascularisation.Kaplan-Meier analysis assessed survival at 12 months by tertiles of rSYNTAX and ΔSYNTAX% scores. Increasing ΔSYNTAX%score was associated with reduced in-hospital mortality(P = 0.017), and improved survival benefit(log rank 14.8, P = 0.001) at 12 months.CONCLUSIONS Enhancing the completeness of revascularisation in octogenarians selected to undergo PCI is associated with a lower in-hospital mortality and a survival benefit at 12 months.