Regulation of apoptotic signal transduction pathways by the heat shock proteins

被引:1
|
作者
LI Zhengyu1
2. Key Laboratory of Biotherapy of Human Diseases of Ministry of Education
机构
关键词
heat shock protein; apoptotic signal transduction; molecular chaperone; caspases;
D O I
暂无
中图分类号
Q51 [蛋白质];
学科分类号
摘要
The study about apoptotic signal transductions has become a project to reveal the molecular mechanisms of apoptosis. Heat shock proteins (hsps), which play an important role in cell growth and apoptosis, have attracted great attentions. A lot of researches have showed there is a hsps superfamily including hsp90, hsp70, hsp60 and hsp27, etc., which regulates the bio-logical behaviors of cells, particularly apoptotic signal transduction in Fas pathway, JNK/SAPK pathway and caspases pathway at different levels, partly by the function of molecular chaperone.
引用
收藏
页码:107 / 114
页数:8
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