Infectivity of SARS-CoV-2 and protection against reinfection in rats

被引：0

作者：

Dandan Yu ^{[1
,2
,3
]}

Yanghaopeng Long ^{[2
]}

Ling Xu ^{[1
,2
,3
]}

Jian-Bao Han ^{[2
]}

Jiawei Xi ^{[1
]}

Jianlin Xu ^{[1
]}

Lu-Xiu Yang ^{[1
]}

Xiao-Li Feng ^{[2
]}

Qing-Cui Zou ^{[2
]}

Wang Qu ^{[2
]}

Jiangwei Lin ^{[1
]}

Ming-Hua Li ^{[2
]}

Yong-Gang Yao ^{[1
,2
,3
]}

机构：

[1] Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences

[2] Kunming National High-Level Biosafety Research Center for Non-Human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences

[3] Kunming College of Life Science, University of Chinese Academy of Sciences

来源：

Zoological Research | 2022年 / 43卷 / 06期

基金：

中国国家自然科学基金;

关键词：

D O I：

暂无

中图分类号：

R563.1 [肺炎]; R-332 [医用实验动物学];

学科分类号：

1001 ; 1002 ; 100201 ;

摘要：

DEAR EDITOR,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) pandemic remains an important global public health issue. In this study, we unexpectedly found that wildtype Sprague-Dawley(SD) rats can be infected with the SARS-CoV-2 prototype. Our results showed direct experimental evidence of the infectivity of SARS-CoV-2 infection, subsequent pathogenicity, and protection against reinfection in rats.

引用

页码：945 / 948

页数：4

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