Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes

被引：0
|
作者：
WERNESS Jenny B [1 ]
TANG WeiPing [2 ]
机构：
[1] Department of Chemistry, University of Wisconsin
[2] School of Pharmacy, University of
来源：
Science China(Chemistry) | 2011年 / 01期
关键词：
D O I：
暂无
中图分类号：
O621.3 [有机合成化学];
学科分类号：
摘要：
The discovery of the novel reactivity of conjugated enynes,mediated by readily available halogenation reagents,opens a broad range of mechanistically unique pathways for the synthesis of highly functionalized chiral allene derivatives.Bromoallenyl pyrrolidines can be synthesized via 1,4-addition of sulfonamide nitrogen nucleophiles and halogens to conjugated enynes.This process can lead to simultaneous formation of a highly functionalized axially chiral allene and a stereogenic center under economical and environmentally friendly reaction conditions.
引用
收藏
页码：56 / 60
页数：5
相关论文
共 50 条
  • [1] Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes
    Jenny B. Werness
    WeiPing Tang
    Science China Chemistry, 2011, 54 : 56 - 60
  • [2] Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes
    Werness, Jenny B.
    Tang WeiPing
    SCIENCE CHINA-CHEMISTRY, 2011, 54 (01) : 56 - 60
  • [3] Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes
    WERNESS Jenny B.
    TANG WeiPing
    Science China(Chemistry), 2011, 54 (01) : 56 - 60
  • [4] Copper/Photoredox-Catalyzed Regioselective 1,4-Addition to 1,3-Enynes: A Convenient Access to Perfluoroalkylated Allenes
    Chen, Ya
    Wang, Quanyuan
    Peng, Keyi
    Cheng, Lilei
    She, Ziyi
    Deng, Guo-Jun
    CHINESE JOURNAL OF CHEMISTRY, 2024, 42 (17) : 2023 - 2028
  • [5] Divergent Synthesis of CF3-Substituted Allenyl Nitriles by Ligand-Controlled Radical 1,2-and 1,4-Addition to 1,3-Enynes
    Wang, Fei
    Wang, Dinghai
    Zhou, Yu
    Liang, Ling
    Lu, Ronghua
    Chen, Pinhong
    Lin, Zhenyang
    Liu, Guosheng
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (24) : 7140 - 7145
  • [6] Recent Advances in the Synthesis of Chiral Allenes via Asymmetric 1,4-Difunctionalization of 1,3-Enynes
    Li, Sijia
    Yuan, Kaiyao
    Zhang, Guozhu
    Guo, Rui
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 27 (30)
  • [7] Highly Construction of Tetrasubstituted Silylallenes via 1,4-Hydrosilylation of 1,3-Enynes
    Huang, Weisheng
    Xu, Liwen
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 41 (11) : 4515 - 4516
  • [8] Synthesis of α-Alkynylnitrones via Hydromagnesiation of 1,3-Enynes with Magnesium Hydride
    Li, Yihang
    Ng, Jia Sheng
    Wang, Bin
    Chiba, Shunsuke
    ORGANIC LETTERS, 2021, 23 (13) : 5060 - 5064
  • [9] Asymmetric 1,4-functionalization of 1,3-enynes via dual photoredox and chromium catalysis
    Feng-Hua Zhang
    Xiaochong Guo
    Xianrong Zeng
    Zhaobin Wang
    Nature Communications, 13
  • [10] Asymmetric 1,4-functionalization of 1,3-enynes via dual photoredox and chromium catalysis
    Zhang, Feng-Hua
    Guo, Xiaochong
    Zeng, Xianrong
    Wang, Zhaobin
    NATURE COMMUNICATIONS, 2022, 13 (01)
12345