Alpha-synuclein in mitochondrial dysfunction: opportunities or obstacles

被引:0
|
作者
Shermali Gunawardena
机构
[1] Department of Biological Sciences
[2] The State University of New York at Buffalo
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中图分类号
R741 [神经病学];
学科分类号
摘要
Recent work suggests a link between α-synuclein(α-syn) and mitochondrial dysfunction; however, the mechanisms of how α-syn influences mitochondrial function are still unclear. Most notably, whether α-syn plays a direct role during mitochondrial function and/or whether diseased α-syn-mediated mitochondrial dysfunction is a potential modifiable risk factor in Parkinson’s disease(PD) is unknown.
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页码:197 / 198
页数:2
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