SELF-ASSEMBLY OF STREPTAVIDIN BISBIOTIN MONOLAYERS AND MULTILAYERS

被引：12

作者：

MORGAN, H

TAYLOR, DM

DSILVA, C

FUKUSHIMA, H

机构：

[1] Institute of Molecular and Biomolecular Electronics, University of Wales, Bangor, Gwynedd LL57 1UT, Dean Street

来源：

THIN SOLID FILMS | 1992年 / 210卷 / 1-2期

关键词：

D O I：

10.1016/0040-6090(92)90400-6

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

It is shown that a solution containing a 2:1 mixture of 1,4-bis(biotinamidomethyl)benzene and streptavidin readily polymerises into rigid, rod-like molecules. The affinity of the protein for the biotin ligand is then exploited in the controlled assembly of a multilayer film of streptavidin approximately 40 nm thick. Surface plasmon resonance measurements confirm that the film is assembled one monolayer at a time.

引用

页码：773 / 775

页数：3

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