DIFFERENCES IN THE ASSOCIATION ABILITIES IN AQUEOUS-SOLUTIONS OF CYTIDINE, 2'-DEOXYCYTIDINE AND THEIR PHOSPHATE SALTS STUDIED BY FOURIER-TRANSFORM INFRARED-SPECTROSCOPY

被引：7

作者：

KULINSKA, K

SARZYNSKA, J

WIEWIOROWSKI, M

机构：

[1] Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznán

来源：

VIBRATIONAL SPECTROSCOPY | 1991年 / 1卷 / 03期

关键词：

INFRARED SPECTROMETRY; NUCLEOSIDES; CYTIDINE; DEOXYCYTIDINE;

D O I：

10.1016/0924-2031(91)85005-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Fourier transform infrared (FT-IR) spectral investigations of Cyd and dCyd nucleosides and their phosphate salts were made in aqueous media in order to determine their association abilities. The observed effects on the FT-IR spectra of increasing concentrations of H2O and D2O solutions indicate drastically different association properties and hydration between the compounds studied in the ribo and deoxyribo series. The results show that examination of biomolecules in their natural environment (aqueous media) by FT-IR spectrometry is feasible and informative with regard to precrystallization phenomena.

引用

页码：277 / 286

页数：10

共 12 条

[1]

BRATEKWIEWIOROW.MD, UNPUB NUCLEOSIDES NU

[2] THE NATURE OF DRASTIC DIFFERENCES IN THE RECOGNITION OF PROTONATED CYTIDINIUM AND DEOXYCYTIDINIUM CATIONS BY THEIR PARENT NUCLEOSIDES WITHIN DIHYDROGENPHOSPHATE SALTS IN THE LIGHT OF THE COMPUTER-SIMULATED CRYSTAL-STRUCTURE OF DCYD HEMIPHOSPHATE (DCYD)2H+H2PO4-] [J].