DEREGULATION OF HAMSTER FIBROBLAST PROLIFERATION BY MUTATED RAS ONCOGENES IS NOT MEDIATED BY CONSTITUTIVE ACTIVATION OF PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE-C

被引:138
作者
SEUWEN, K
LAGARDE, A
POUYSSEGUR, J
机构
[1] UNIV TORONTO,DEPT MED GENET,TORONTO MC5 1X5,ONTARIO,CANADA
[2] MT SINAI HOSP,RES INST,DIV CANC & CELL BIOL,TORONTO M5G 1X5,ONTARIO,CANADA
关键词
D O I
10.1002/j.1460-2075.1988.tb02796.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:161 / 168
页数:8
相关论文
共 43 条
[1]   THE RAS ONCOGENE PRODUCT P21 IS NOT A REGULATORY COMPONENT OF ADENYLATE-CYCLASE [J].
BECKNER, SK ;
HATTORI, S ;
SHIH, TY .
NATURE, 1985, 317 (6032) :71-72
[2]   LOSS OF PLATELET-DERIVED GROWTH FACTOR-STIMULATED PHOSPHOLIPASE-ACTIVITY IN NIH-3T3 CELLS EXPRESSING THE EJ-RAS ONCOGENE [J].
BENJAMIN, CW ;
TARPLEY, WG ;
GORMAN, RR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) :546-550
[3]   INOSITOL TRISPHOSPHATE, A NOVEL 2ND MESSENGER IN CELLULAR SIGNAL TRANSDUCTION [J].
BERRIDGE, MJ ;
IRVINE, RF .
NATURE, 1984, 312 (5992) :315-321
[4]   FLUOROALUMINATES ACTIVATE TRANSDUCIN-GDP BY MIMICKING THE GAMMA-PHOSPHATE OF GTP IN ITS BINDING-SITE [J].
BIGAY, J ;
DETERRE, P ;
PFISTER, C ;
CHABRE, M .
FEBS LETTERS, 1985, 191 (02) :181-185
[5]   2 GROWTH-FACTOR SIGNALING PATHWAYS IN FIBROBLASTS DISTINGUISHED BY PERTUSSIS TOXIN [J].
CHAMBARD, JC ;
PARIS, S ;
LALLEMAIN, G ;
POUYSSEGUR, J .
NATURE, 1987, 326 (6115) :800-803
[6]   ROLE OF GUANINE-NUCLEOTIDE BINDING-PROTEIN IN THE ACTIVATION OF POLYPHOSPHOINOSITIDE PHOSPHODIESTERASE [J].
COCKCROFT, S ;
GOMPERTS, BD .
NATURE, 1985, 314 (6011) :534-536
[7]   EXTREME INSTABILITY OF MYC MESSENGER-RNA IN NORMAL AND TRANSFORMED HUMAN-CELLS [J].
DANI, C ;
BLANCHARD, JM ;
PIECHACZYK, M ;
ELSABOUTY, S ;
MARTY, L ;
JEANTEUR, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (22) :7046-7050
[8]   INSULIN RAPIDLY INCREASES DIACYLGLYCEROL BY ACTIVATING DENOVO PHOSPHATIDIC-ACID SYNTHESIS [J].
FARESE, RV ;
KONDA, TS ;
DAVIS, JS ;
STANDAERT, ML ;
POLLET, RJ ;
COOPER, DR .
SCIENCE, 1987, 236 (4801) :586-589
[9]   RAS-TRANSFORMED CELLS - ALTERED LEVELS OF PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE AND CATABOLITES [J].
FLEISCHMAN, LF ;
CHAHWALA, SB ;
CANTLEY, L .
SCIENCE, 1986, 231 (4736) :407-410
[10]   MONOCLONAL-ANTIBODIES TO THE P21 PRODUCTS OF THE TRANSFORMING GENE OF HARVEY MURINE SARCOMA-VIRUS AND OF THE CELLULAR RAS GENE FAMILY [J].
FURTH, ME ;
DAVIS, LJ ;
FLEURDELYS, B ;
SCOLNICK, EM .
JOURNAL OF VIROLOGY, 1982, 43 (01) :294-304