Recurrence of Cryptococcal Meningitis and the Hidden Role of Patient Education and Social Support

被引:3
作者
Bongomin, Felix [1 ]
Atikoro, Lorna [2 ]
机构
[1] Gulu Univ, Fac Med, Dept Med Microbiol & Immunol, POB 166, Gulu, Uganda
[2] Gulu Reg Referral Hosp, Dept Med, POB 180, Gulu, Uganda
关键词
D O I
10.1155/2018/8125096
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Human immunodeficiency virus-(HIV-) associated cryptococcal meningitis (CM) is one of the leading causes of deaths among patients living with HIV/AIDS in resource-limited settings, accounting for similar to 15-20% of AIDS-related deaths globally. We present our experience with a 25-year-old woman living with HIV who had a recurrent cryptococcal disease due to nonadherence to HIV care and lack of awareness of the benefits of adherence to secondary prophylaxis for CM. This case highlights the fact that fungal diseases awareness should not be limited only to the health professionals and public health practitioners, but also to patients, caregivers, and stakeholders.
引用
收藏
页数:4
相关论文
共 21 条
[1]   Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis [J].
Beardsley, J. ;
Wolbers, M. ;
Kibengo, F. M. ;
Ggayi, A. -B. M. ;
Kamali, A. ;
Cuc, N. T. K. ;
Binh, T. Q. ;
Chau, N. V. V. ;
Farrar, J. ;
Merson, L. ;
Phuong, L. ;
Thwaites, G. ;
Van Kinh, N. ;
Thuy, P. T. ;
Chierakul, W. ;
Siriboon, S. ;
Thiansukhon, E. ;
Onsanit, S. ;
Supphamongkholchaikul, W. ;
Chan, A. K. ;
Heyderman, R. ;
Mwinjiwa, E. ;
van Oosterhout, J. J. ;
Imran, D. ;
Basri, H. ;
Mayxay, M. ;
Dance, D. ;
Phimmasone, P. ;
Rattanavong, S. ;
Lalloo, D. G. ;
Day, J. N. .
NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (06) :542-554
[2]   Symptomatic relapse of HIV-associated cryptococcal meningitis after initial fluconazole monotherapy: The role of fluconazole resistance and immune reconstitution [J].
Bicanic, Tihana ;
Harrison, Thomas ;
Niepieklo, Alina ;
Dyakopu, Nontobeko ;
Meintjes, Graeme .
CLINICAL INFECTIOUS DISEASES, 2006, 43 (08) :1069-1073
[3]   A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species [J].
Bongomin, Felix ;
Oladele, Rita O. ;
Gago, Sara ;
Moore, Caroline B. ;
Richardson, Malcolm D. .
MYCOSES, 2018, 61 (05) :290-297
[4]   A PLACEBO-CONTROLLED TRIAL OF MAINTENANCE THERAPY WITH FLUCONAZOLE AFTER TREATMENT OF CRYPTOCOCCAL MENINGITIS IN THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].
BOZZETTE, SA ;
LARSEN, RA ;
CHIU, J ;
LEAL, MAE ;
JACOBSEN, J ;
ROTHMAN, P ;
ROBINSON, P ;
GILBERT, G ;
MCCUTCHAN, JA ;
TILLES, J ;
LEEDOM, JM ;
RICHMAN, DD .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (09) :580-584
[5]  
Day JN, 2013, NEW ENGL J MED, V368, P1291, DOI [10.1056/NEJMoa1110404, 10.1056/NEJMc1305981]
[6]   Evolving Failures in the Delivery of Human Immunodeficiency Virus Care: Lessons From a Ugandan Meningitis Cohort 2006-2016 [J].
Flynn, Andrew G. ;
Meya, David B. ;
Hullsiek, Katherine Huppler ;
Rhein, Joshua ;
Williams, Darlisha A. ;
Musubire, Abdu ;
Morawski, Bozena M. ;
Taseera, Kabanda ;
Sadiq, Alisat ;
Ndyatunga, Liberica ;
Roediger, Mollie ;
Rajasingham, Radha ;
Bohjanen, Paul R. ;
Muzoora, Conrad ;
Boulware, David R. .
OPEN FORUM INFECTIOUS DISEASES, 2017, 4 (02)
[7]   The Enduring Challenge of Advanced HIV Infection [J].
Ford, Nathan ;
Doherty, Meg .
NEW ENGLAND JOURNAL OF MEDICINE, 2017, 377 (03) :283-284
[8]   HIV-associated cryptococcal meningitis [J].
Jarvis, Joseph N. ;
Harrison, Thomas S. .
AIDS, 2007, 21 (16) :2119-2129
[9]   Global access to antifungal therapy and its variable cost [J].
Kneale, Matthew ;
Bartholomew, Jennifer S. ;
Davies, Emma ;
Denning, David W. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2016, 71 (12) :3599-3606
[10]  
Lalloo U.G., 2018, P C RETR OPP INF CRO