A NOVEL-APPROACH TO THE ASYMMETRIC-SYNTHESIS OF MANZAMINE-A - CONSTRUCTION OF THE TETRACYCLIC ABCE RING-SYSTEM

被引：107

作者：

MARTIN, SF

LIAO, YS

WONG, YL

REIN, T

机构：

[1] Department of Chemistry and Biochemistry, The University of Texas, Austin

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 05期

关键词：

D O I：

10.1016/S0040-4039(00)75792-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantiomerically pure tetracyclic ABCE subunit of manzamine A has been constructed by an intramolecular Diels-Alder reaction of the vinylogous imide 13 to give the ABC tricyclic core 14; elaboration of 14 into 16 followed by a novel olefin metathesis reaction to form the azocine ring then delivered the tetracycle 17.

引用

页码：691 / 694

页数：4

共 29 条

[1] STEREOCONTROL IN THE INTRAMOLECULAR DIELS-ALDER REACTION .3. A POTENTIALLY GENERAL-METHOD FOR THE SYNTHESIS OF CIS-HYDRINDENES BY USE OF (Z)-DIENE UNITS [J].