Data on the effects of remote ischemic preconditioning in the lungs after one-lung ventilation

被引:4
作者
Bergmann, Astrid [1 ,2 ]
Breitling, Christian [1 ]
Hedenstierna, Goran [2 ]
Larsson, Anders [3 ]
Kretzschmar, Moritz [1 ]
Kozian, Alf [1 ]
Hachenberg, Thomas [1 ]
Schilling, Thomas [1 ]
机构
[1] Otto von Guericke Univ, Dept Anesthesiol & Intens Care Med, Magdeburg, Germany
[2] Uppsala Univ, Hedenstierna Lab, Dept Med Sci, Uppsala, Sweden
[3] Uppsala Univ, Hedenstierna Lab, Dept Surg Sci, Uppsala, Sweden
来源
DATA IN BRIEF | 2018年 / 21卷
基金
瑞典研究理事会;
关键词
Animal model; One-lung ventilation; Remote ischemic preconditioning; Diffuse alveolar damage; Pulmonary inflammatory response;
D O I
10.1016/j.dib.2018.09.085
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
This article contains data on experimental endpoints of a randomized controlled animal trial. Fourteen healthy piglets underwent mechanical ventilation including injurious one-lung ventilation (OLV), seven of them experienced four cycles of remote ischemic preconditioning (RIP) on one hind limb immediately before OLV, seven of them did not receive RIP and served as controls, in a randomized manner. The two major endpoints were (1) pulmonary damage assessed with the diffuse alveolar damage (DAD) score and (2) the inflammatory response assessed by cytokine concentrations in serum and in bronchoalveolar lavage fluids (BAL). The cytokine levels in the homogenized lung tissue samples are presented in the original article. Further interpretation and discussion of these data can be found in Bergmann et al. (in press). (C) 2018 The Authors. Published by Elsevier Inc.
引用
收藏
页码:441 / 448
页数:8
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