THE EFFECT OF IMMUNE AND INFLAMMATORY MEDIATORS ON GROWTH OF LUCILIA-CUPRINA LARVAE IN-VITRO

被引：4

作者：

COLDITZ, IG ^{[1
]}

EISEMANN, CH ^{[1
]}

机构：

[1] CSIRO,DIV TROP ANIM PROD,LONG POCKET LABS,INDOOROOPILLY,QLD 4068,AUSTRALIA

来源：

INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1994年 / 24卷 / 03期

关键词：

LUCILIA-CUPRINA; LARVAL GROWTH; CYTOKINES; INFLAMMATORY MEDIATORS; IMMUNE RESISTANCE;

D O I：

10.1016/0020-7519(94)90088-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Immune and inflammatory responses occurring during dermal infestation by larvae of Lucilia cuprina can retard larval growth and development. This study examined the effect of 4 classes of humoral inflammatory mediators on larval growth in an in vitro assay. Mediators of plasma leakage (histamine, bradykinin, platelet-activating factor and serotonin), leucocyte chcmotactic agonists (activated complement, leukotriene B4 and interleukin-8), effector molecules of immune responses (interleukin-1beta tumour necrosis factor-alpha and interferon-gamma) and endotoxin all failed to inhibit larval growth. In contrast, immunoglobulins isolated from immune serum caused marked retardation of larval growth. The results suggest that humoral mediators of inflammatory and immune responses do not play a role in immune defence against Lucilia cuprina.

引用

页码：401 / 403

页数：3

共 13 条

[1] CELLULAR IMMUNE-RESPONSES IN THE SKIN OF SHEEP INFECTED WITH LARVAE OF LUCILIA-CUPRINA, THE SHEEP BLOWFLY
BOWLES, VM
GREY, ST
BRANDON, MR
[J]. VETERINARY PARASITOLOGY, 1992, 44 (1-2) : 151 - 162
[2] PLASMA LEAKAGE IN SKIN OF SHEEP SELECTED FOR RESISTANCE OR SUSCEPTIBILITY TO FLEECE ROT AND FLY STRIKE
COLDITZ, IG
WOOLASTON, RR
LAX, J
MORTIMER, SI
[J]. PARASITE IMMUNOLOGY, 1992, 14 (06) : 587 - 594
[3] COLDITZ IG, 1992, IMMUNOLOGY, V76, P272
[4] THE INDUCTION OF PLASMA LEAKAGE IN SKIN BY HISTAMINE, BRADYKININ, ACTIVATED COMPLEMENT, PLATELET-ACTIVATING-FACTOR AND SEROTONIN
COLDITZ, IG
[J]. IMMUNOLOGY AND CELL BIOLOGY, 1991, 69 : 215 - 219
[5] DRYSDALE BE, 1988, PROG ALLERGY, V40, P111
[6] LUCILIA-CUPRINA - INHIBITION OF LARVAL GROWTH INDUCED BY IMMUNIZATION OF HOST SHEEP WITH EXTRACTS OF LARVAL PERITROPHIC MEMBRANE
EAST, IJ
FITZGERALD, CJ
PEARSON, RD
DONALDSON, RA
VUOCOLO, T
CADOGAN, LC
TELLAM, RL
EISEMANN, CH
[J]. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1993, 23 (02) : 221 - 229
[7] THE PERITROPHIC MEMBRANE - ITS FORMATION, STRUCTURE, CHEMICAL-COMPOSITION AND PERMEABILITY IN RELATION TO VACCINATION AGAINST ECTOPARASITIC ARTHROPODS
EISEMAN, CH
BINNINGTON, KC
[J]. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1994, 24 (01) : 15 - 26
[8] RETARDED GROWTH OF LUCILIA-CUPRINA LARVAE ON SHEEP AND THEIR SERA FOLLOWING PRODUCTION OF AN IMMUNE-RESPONSE
JOHNSTON, LAY
EISEMANN, CH
DONALDSON, RA
PEARSON, RD
VUOCOLO, T
[J]. INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1992, 22 (02) : 187 - 193
[9] CHANGES IN PROTEIN CONCENTRATION AND BACTERIA OF FLEECE AND SKIN DURING THE DEVELOPMENT OF FLEECE-ROT AND BODY STRIKE IN SHEEP
MERRITT, GC
WATTS, JE
[J]. AUSTRALIAN VETERINARY JOURNAL, 1978, 54 (11) : 517 - 520
[10] VARIATION IN SKIN INFLAMMATORY RESPONSES BETWEEN SHEEP BRED FOR RESISTANCE OR SUSCEPTIBILITY TO FLEECE ROT AND BLOWFLY STRIKE
OMEARA, TJ
NESA, M
RAADSMA, HW
SAVILLE, DG
SANDEMAN, RM
[J]. RESEARCH IN VETERINARY SCIENCE, 1992, 52 (02) : 205 - 210

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